ChemicalBook >> CAS DataBase List >>2'-O-Methyluridine

2'-O-Methyluridine

CAS No.
2140-76-3
Chemical Name:
2'-O-Methyluridine
Synonyms
1-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxyMethyl)-3-Methoxytetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione;OMe-rU;2'-OMe-Ur;2'-OMe-rU;2'-OMe Uridine;2-Methyoxy uridine;2'-O-METHYLURIDINE;2'-O-Methyluridine;2 '- Methoxyuridine;2'-O-Methyluridine>
CBNumber:
CB8397539
Molecular Formula:
C10H14N2O6
Molecular Weight:
258.23
MDL Number:
MFCD00056054
MOL File:
2140-76-3.mol
Last updated:2023-05-18 11:31:15

2'-O-Methyluridine Properties

Melting point 154-156°C
Density 1.53±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
pka 9.39±0.10(Predicted)
form Powder
color White to Off-white
λmax 261nm(MeOH)(lit.)
CAS DataBase Reference 2140-76-3(CAS DataBase Reference)
FDA UNII 399VZB6TMB

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301-H311-H331
Precautionary statements  P261-P264-P270-P271-P280-P302+P352-P304+P340-P310-P330-P361-P403+P233-P405-P501
Hazard Codes  T+
Risk Statements  26/27/28
Safety Statements  24/25
HS Code  29389090

2'-O-Methyluridine price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical M2290 2'-O-Methyluridine >98.0%(HPLC)(T) 2140-76-3 1g $65 2024-03-01 Buy
TCI Chemical M2290 2'-O-Methyluridine >98.0%(HPLC)(T) 2140-76-3 5g $195 2024-03-01 Buy
Alfa Aesar J64897 2'-O-Methyluridine, 99% 2140-76-3 1g $33.3 2023-06-20 Buy
TRC M338200 2''-O-MethylUridine 2140-76-3 50g $1245 2021-12-16 Buy
Biosynth Carbosynth NM04259 2'-O-Methyluridine 2140-76-3 50g $350 2021-12-16 Buy
Product number Packaging Price Buy
M2290 1g $65 Buy
M2290 5g $195 Buy
J64897 1g $33.3 Buy
M338200 50g $1245 Buy
NM04259 50g $350 Buy

2'-O-Methyluridine Chemical Properties,Uses,Production

Description

2'-O-Methyluridine is an analog of uridine and has been shown to have antiviral and anticancer properties. 2'-O-Methyluridine inhibits protein synthesis by competing with uridine for the active site of the enzyme ribonucleotide reductase, which converts ribonucleotides to dNMPs. This compound also inhibits RNA synthesis by disrupting the pairing of adenine and cytosine residues in RNA strands.

Chemical Properties

White Solid

Uses

Uridine analog. 2'-O-Methyluridine is used for preparation of antiviral nucleoside derivatives as inhibitors of subgenomic hepatitis C virus RNA replication.

Uses

Uridine analog. Used for preparation of antiviral nucleoside derivatives as inhibitors of subgenomic hepatitis C virus RNA replication.

Definition

ChEBI: A methyluridine that consists of uridine bearing a single methyl substituent located at position O-2' on the ribose ring.

1384271-34-4
2140-76-3
Synthesis of 2'-O-Methyluridine from Uridine, 2'-O-methyl-3-[(phenylmethoxy)methyl]-3'-O-(phenylmethyl)-

2'-O-Methyluridine Preparation Products And Raw materials

Global( 321)Suppliers
Supplier Tel Email Country ProdList Advantage
Wuhu Nuowei chemistry Co., Ltd.
+86-0553-2911116-802 +undefined17756524438 sales1@nuowei-chem.com China 1642 58
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 product@chemlin.com.cn CHINA 3012 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830 figo.gao@foxmail.com China 7019 58
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Yunbio Tech Co.,Ltd.
+86-010-60605551 +86-18046518538 yunbiochem@126.com China 321 58
Xiamen AmoyChem Co., Ltd
+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58
Nanjing Baifuli Technology Co., Ltd.
+86-15335185688 sales@unisyn.cn CHINA 332 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58

View Lastest Price from 2'-O-Methyluridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2'-O-Methyluridine pictures 2023-04-04 2'-O-Methyluridine
2140-76-3
US $0.00-0.00 / kg 1kg 98% 500kg per month Zhejiang Hengkang Pharmaceutical Co., Ltd.
2'-OME-rU pictures 2023-03-24 2'-OME-rU
2140-76-3
US $0.00 / g 100g ≥98%(HPLC) 20t Hefei Huana Biomedical Technology Co.,Ltd.
2'-O-Me-Uridine;2'-OMe-U pictures 2023-03-22 2'-O-Me-Uridine;2'-OMe-U
2140-76-3
US $100.00 / kg 0.009999999776482582kg 99% 5tons SHANGHAI NOVRIBO BIOTECH
  • 2'-O-Methyluridine pictures
  • 2'-O-Methyluridine
    2140-76-3
  • US $0.00-0.00 / kg
  • 98%
  • Zhejiang Hengkang Pharmaceutical Co., Ltd.
  • 2'-OME-rU pictures
  • 2'-OME-rU
    2140-76-3
  • US $0.00 / g
  • ≥98%(HPLC)
  • Hefei Huana Biomedical Technology Co.,Ltd.

2'-O-Methyluridine Spectrum

2'-O-METHYLURIDINE (CHIRAL) 2''-O-METHYLURIDINE CRYSTALLINE 1-[(2R,3R,4R,5R)-4-hydroxy-3-methoxy-5-methylol-tetrahydrofuran-2-yl]pyrimidine-2,4-quinone 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-oxolan-2-yl]pyrimidine-2,4-dione 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione 2'-O-METHYLURIDINE 2-Methyoxy uridine 1-[(2S,3S,4R,5S)-4-hydroxy-5-(hydroxyMethyl)-3-Methoxyoxolan-2-yl]-1,2,3,4-tetrahydropyriMidine-2,4-dione 1-(2-O-Methyl-beta-D-ribofuranosyl)uracil 2'-O-Methyluridine USP/EP/BP 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione 1-[(2R,3R,4R,5R)-4-HYDROXY-5-(HYDROXYMETHYL)-3-METHOXYOXOLAN-2-YL]-3H-PYRIMIDINE-2,4-DIONE 2'-O-Methyluridine 98+% 2'-O-Methyluridine, 98.0 % 2'-OMe-Ur 2'-O-Methyluridine> Uridine, 2'-O-methyl- 2'-OMe-rU 1-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxyMethyl)-3-Methoxytetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione 2’-O-Methyl uridine, RNA modified nucleoside Um RNA modified nucleoside Um 1-((2S,3S,4S,5S)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 2 '- Methoxyuridine OMe-rU 2'-O-Methyluridine 2'-OMe Uridine 2140-76-3 2140-79-3 2104-76-3 pyrimidine Heterocycle-Pyrimidine series Bases & Related Reagents Carbohydrates & Derivatives Heterocycles Nucleotides Pharmaceutical 2140-76-3 Nucleosides Modified(deoxy)nucleoside