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4-Chloro-4'-hydroxybenzophenone

CAS No.
42019-78-3
Chemical Name:
4-Chloro-4'-hydroxybenzophenone
Synonyms
4-CHLORO-4-HYDROXYBENZOPHENONE;NSC4056;NSC 4056;NSC-4056;4-Chloro-4'-;4-Chloro-4'EP-A /USP RC A;4-Chloro-4'-hydroxyb;-hydroxybenzophenone;LABOTEST-BB LT00248477
CBNumber:
CB8435031
Molecular Formula:
C13H9ClO2
Molecular Weight:
232.66
MDL Number:
MFCD00002357
MOL File:
42019-78-3.mol
MSDS File:
SDS
Last updated:2024-04-22 15:07:34

4-Chloro-4'-hydroxybenzophenone Properties

Melting point 177-181 °C
Boiling point 257 °C (13 mmHg)
Density 1.2082 (rough estimate)
refractive index 1.5434 (estimate)
Flash point 100 °C
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
pka 7.68±0.15(Predicted)
color Pale Beige to Light Brown
BRN 2049956
CAS DataBase Reference 42019-78-3(CAS DataBase Reference)
FDA UNII FF9YB926A3
NIST Chemistry Reference Methanone, (4-chlorophenyl)(4-hydroxyphenyl)-(42019-78-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P305+P351+P338-P261-P280a-P304+P340-P405-P501a
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22
Safety Statements  24/25-37/39-26-36
Hazard Note  Irritant
HS Code  29144000
NFPA 704
0
0 0

4-Chloro-4'-hydroxybenzophenone price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2864 Fenofibrate Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material 42019-78-3 50MG $718 2024-03-01 Buy
Sigma-Aldrich F0048005 Fenofibrate impurity A European Pharmacopoeia (EP) Reference Standard 42019-78-3 f0048005 $153 2024-03-01 Buy
Sigma-Aldrich 1269607 Fenofibrate Related Compound A United States Pharmacopeia (USP) Reference Standard 42019-78-3 25mg $894 2024-03-01 Buy
TCI Chemical C1155 4-Chloro-4'-hydroxybenzophenone >98.0%(GC) 42019-78-3 25g $75 2024-03-01 Buy
TCI Chemical C1155 4-Chloro-4'-hydroxybenzophenone >98.0%(GC) 42019-78-3 500g $576 2024-03-01 Buy
Product number Packaging Price Buy
PHR2864 50MG $718 Buy
F0048005 f0048005 $153 Buy
1269607 25mg $894 Buy
C1155 25g $75 Buy
C1155 500g $576 Buy

4-Chloro-4'-hydroxybenzophenone Chemical Properties,Uses,Production

Chemical Properties

light grey to beige-brown powder

Uses

4-Chloro-4’-hydroxybenzophenone (Fenofibrate EP Impurity A; Fenofibrate USP Related Compound A) the impurity of Fenofibric acid (42017-89-0), the active metabolite of fenofibrate which increases Apolipoprotein A-I–Mediated High-Density Lipoprotein Biogenesis by enhancing transcription of ATP-Binding cassette transporter A1 gene in a liver X receptor–dependent manner.

Preparation

Preparation by Fries rearrangement of phenyl p-chloro-benzoate,
? in the presence of aluminium chloride, without solvent, at 160° for 5 min, between 120° and 160° (good yield) or at 130° for 1 h, then at 160° for 1 h (10%) or in refluxing chlorobenzene for 10 h (52%);
? in the presence of trifluoromethanesulfonic acid at 45–55° (94%).

623-03-0
108-95-2
42019-78-3
Synthesis of 4-Chloro-4'-hydroxybenzophenone from 4-Chlorobenzonitrile and Phenol
Global( 552)Suppliers
Supplier Tel Email Country ProdList Advantage
Firsky International Trade (Wuhan) Co., Ltd
+8615387054039 admin@firsky-cn.com China 436 58
Ouhuang Engineering Materials (Hubei) Co., Ltd
+8617702722807 admin@hbouhuang.com China 2259 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15928 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +86-18949832763 info@tnjchem.com China 2989 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Jinan Finer Chemical Co., Ltd
+86-531-88989536 +86-15508631887 sales@finerchem.com China 2967 58
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58

View Lastest Price from 4-Chloro-4'-hydroxybenzophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-p-Chlorobenzoylphenol pictures 2024-04-22 4-p-Chlorobenzoylphenol
42019-78-3
US $30.00 / kg 1kg 99.7% 200000kg Ouhuang Engineering Materials (Hubei) Co., Ltd
4-Chloro-4′-Hydroxybenzophenone pictures 2024-01-08 4-Chloro-4′-Hydroxybenzophenone
42019-78-3
US $15.00-10.00 / g 1g 99.50% 10kg Wuhan Boyuan Import & Export Co., LTD
4-Chloro-4'-hydroxybenzophenone pictures 2023-10-08 4-Chloro-4'-hydroxybenzophenone
42019-78-3
US $30.00 / KG 1KG 99% 20T Firsky International Trade (Wuhan) Co., Ltd
4-hydroxy-4’-chloro-benophenone 4-Chloro-4'-Hydroxybenzophenone 4-Hydroxy-4'-Chlorobenzophenone 4-p-Chlorobenzoylphenol 4-(4-Chlorobenzoyl)-4-Hydroxypiperidine 4-(4-CHLOROBENZOYL)PHENOL 4-Chloro-4'-hydroxybenzophenon LABOTEST-BB LT00248477 METHANONE, (4-CHLOROPHENYL)(4-HYDROXYPHENYL)- 4-CHLORO-4'-HYDROXYBENZOPHENONE 4-HYDROXY-4'-CHLOROBENZOPHENONE (4-CHLORO-PHENYL)-(4-HYDROXY-PHENYL)-METHANONE 4-CHLORO-4''-HYDROXYBENZOPHENONE=99.0% 8) 4-CHLORO 4-HYDROXY BENZOPHENONE 4-CHLORO-4''-HYDROXYBENZOPHENONEFENOFIBRATE 4,4'-Chlorohydroxybenzophenone 4-Chloro-4'-hydroxybenzophenone,98% 4-Chloro-4'-hydroxyb Fenofibrate Related Compound A (25 mg) ((4-chlorophenyl)(4-hydroxyphenyl)methanone) (4-chlorophenyl)(4-hydroxyphenyl)MethaNAne Fenofibrate EP IMpurity A Chloro-4'-hydroxybenzophe -4'-two4-chlorinehydroxylbenzophenone Fenofibrate Related Compound A (4-Chloro-4'-Hydroxybenzophenone) 4-Chloro-4'-hydroxybenzophenone≥ 99% (GC) 1-(4-Chlorophenyl)-1-(4-hydroxyphenyl)methanone Benzophenone,4-chloro-4'-hydroxy- (6CI) Fenofibrate Impurity Ⅰ:4-Chloro-4'-hydroxybenzophenone Choline Fenofibrate Impurity A Fenofibrate impurity A (EP) -G Fenofibrate impurity A (EP) 4-Chloro-4'-hydroxybenzoph Fenofibrate Impurity 1(Fenofibrate EP Impurity A) 4-Chloro-4'-hydroxybenzophenone benzophenone 4-Chloro-4'- 4-Chloro-4'-hydroxybenzophenone> Fenofibrate impurity A CRS Fenofibrate Related Impurity A Fenofibrate EP Impurity A/ Fenofibrate Related Compound A Fenofibrate EP Impurity AQ: What is Fenofibrate EP Impurity A Q: What is the CAS Number of Fenofibrate EP Impurity A Q: What is the storage condition of Fenofibrate EP Impurity A Q: What are the applications of Fenofibrate EP Impurity A Fenofibrate impurity A (F0048005) Fenofibrate Impurity 2 Fenofibrate Related Compound A ((4-chlorophenyl)(4-hydroxyphenyl)methanone) (1269607) NSC 4056 NSC4056 NSC-4056 4-CHLORO-4-HYDROXYBENZOPHENONE Choline Fenofibrate EP Impurity A Fenofibrate USP Related Compound A -hydroxybenzophenone 4-Chloro-4' 5-Chloro-4’-hydroxybenzophenone EP-A /USP RC A 4-Chloro-4'-hydroxybenzophenone 42019-78-3 42019-78-2 420-78-3 42109-78-3 ClC6H4COC6H4OH