ChemicalBook >> CAS DataBase List >>Trifluorothymine
Trifluorothymine
- CAS No.
- 54-20-6
- Chemical Name:
- Trifluorothymine
- Synonyms
- 5-(TRIFLUOROMETHYL)URACIL;TRIFLUOROMETHYLURACIL;5-(trifluoroMethyl)pyriMidine-2,4-diol;5-(Trifluoromethyl)pyrimidine-2,4(1H,3H)-dione;5-Trifluoromethyl;2,4-DIHYDROXY-5-TRIFLUOROMETHYL-1H-PYRIMIDINE;L 595725-0-1;TRIFLUOROTHYMINE;5-Trifluorothymine;Trifluorothymine 5-
- CBNumber:
- CB8684875
- Molecular Formula:
- C5H3F3N2O2
- Molecular Weight:
- 180.08
- MDL Number:
- MFCD00006024
- MOL File:
- 54-20-6.mol
- MSDS File:
- SDS
Last updated:2024-04-09 22:15:29
| Melting point | 245-246 °C(lit.) |
|---|---|
| Density | 1.5484 (estimate) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | methanol: soluble50mg/mL, clear |
| form | powder to crystal |
| pka | 6.63±0.10(Predicted) |
| color | White to Orange to Green |
| Water Solubility | INSOLUBLE |
| BRN | 612694 |
| InChIKey | LMNPKIOZMGYQIU-UHFFFAOYSA-N |
| CAS DataBase Reference | 54-20-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 4U846R5P34 |
| NIST Chemistry Reference | 2,4(1H,3h)-pyrimidinedione, 5-(trifluoromethyl)-(54-20-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H319-H335 | |||||||||
| Precautionary statements | P301+P310+P330-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,T | |||||||||
| Risk Statements | 22-36/38-40-36/37/38-25 | |||||||||
| Safety Statements | 24/25-36-26 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | YR1750000 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | Ⅲ | |||||||||
| HS Code | 29335990 | |||||||||
| Toxicity | LD50 intraperitoneal in mouse: 800mg/kg | |||||||||
| NFPA 704 |
|
Trifluorothymine price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 223271 | Trifluorothymine 97% | 54-20-6 | 250mg | $26.6 | 2024-03-01 | Buy |
| TCI Chemical | T1622 | 5-(Trifluoromethyl)uracil >97.0%(HPLC) | 54-20-6 | 1g | $74 | 2024-03-01 | Buy |
| TCI Chemical | T1622 | 5-(Trifluoromethyl)uracil >97.0%(HPLC) | 54-20-6 | 5g | $213 | 2024-03-01 | Buy |
| Alfa Aesar | L16196 | 5-(Trifluoromethyl)uracil, 97% | 54-20-6 | 250mg | $43.4 | 2021-12-16 | Buy |
| Alfa Aesar | L16196 | 5-(Trifluoromethyl)uracil, 97% | 54-20-6 | 1g | $112 | 2021-12-16 | Buy |
Trifluorothymine Chemical Properties,Uses,Production
Chemical Properties
White to faintly yellow crystalline powder
Uses
Trifluorothymine is an antitumor and antiviral agent. Trifluorothymine was found in patientsтАЩ urine as a metabolite of Trifluorothymidine as cancer treatment.
Application
Trifluorothymine (5-(Trifluoromethyl)uracil) is an application medicine intermediate widely. It may be used for the synthesis of the cancer therapy drug trifluridine and also can be used for the preparation of the 2, 4-dichloro-5-trifluoromethyluracil.
Synthesis
Uracil and sodium triflate can be used as raw materials to synthesize Trifluorothymine. This reaction uses a mixed solvent of methylene chloride and water as the reaction solvent and tert-butyl hydroperoxide as the catalyst.
Trifluorothymine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 375)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Yunbio Tech Co.,Ltd. | +86-010-60605551 +86-18046518538 | yunbiochem@126.com | China | 321 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7845 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ | sales03@shyrchem.com | CHINA | 738 | 60 |
| Fluoropharm Co., Ltd. | +86-0571-85586753; +8613336034509 | sales@fluoropharm.com | China | 1290 | 60 |
View Lastest Price from Trifluorothymine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-10 | Trifluorothymine
54-20-6
|
US $0.00 / kg | 1kg | 99% | 1000KG | Shanghai Joiny Pharmaceutical Co.,LTD | |
 |
2024-04-09 | Trifluorothymine
54-20-6
|
US $5.00-0.10 / KG | 1KG | 98% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2023-08-16 | Trifluorothymine
54-20-6
|
US $1.00 / kg | 1kg | >99% | 300000T | Weijer International Trade (Hebei) Co., Ltd |
-
- Trifluorothymine
54-20-6
- US $0.00 / kg
- 99%
- Shanghai Joiny Pharmaceutical Co.,LTD
-
- Trifluorothymine
54-20-6
- US $5.00-0.10 / KG
- 98%
- Henan Fengda Chemical Co., Ltd
-
- Trifluorothymine
54-20-6
- US $1.00 / kg
- >99%
- Weijer International Trade (Hebei) Co., Ltd
54-20-6(Trifluorothymine)Related Search:
(Trifluoromethyl)trimethylsilane
3-(Trifluoromethyl)benzaldehyde
3-（trifluoromethyl) Cinnamaldehyde
Trifluoromethanesulfonic acid
Trifluoromethanesulfonic anhydride
3-(Trifluoromethyl)benzoic acid
2-Methylbenzotrifluoride
[2-13C,15N2]-Trifluorothymine
Trifluridine Impurity
Trifluridine
1of4
5-TRIFLUOROMETHYL-1H-PYRIMIDIN-2,4-DIONE
5-(TRIFLUOROMETHYL)URACIL: 98.5%
5-(Trifluoromethyl)uracil,99%
5-TRIFLUORMETHYL-URACIL
1,3,6-trifluoro-5-Methyl-1,2,3,4-tetrahydropyriMidine-2,4-dione
2,4(1H,3H)-PyriMidinedione,5-(trifluoroMethyl)-
5-(Trifluoromethyl)pyrimidine-2,4(1H,3H)-dione, 2,4-Dioxo-1,2,3,4-tetrahydro-5-(trifluoromethyl)pyrimidine
5-Trifluoromethyluracil≥ 98% (HPLC)
TRIFLUOROTHYMINE
1,2,3,4-Tetrahydropyrazin-2,4-dione, 5-trifluoromethyl-
3h)-pyrimidinedione,5-(trifluoromethyl)-4(1h
5-(Trifluoromethyl)-2,4(1H,3H)-pyrimidinedione
5-(trifluoromethyl)-uraci
L 595725-0-1
Uracil, 5-(trifluoromethyl)-
5-(Trifluoromethyl)uracil98%
Trifluorothymine###2,4-Dichloro-5-trichloromethylpyrimidine
5-(trifluoromethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione
TRIFLUOROMETHYLURACIL CRYSTALLINE
5-(Trifluoromethyl)uracil,97%
TRIFLUOROTHYMINE(RS20000094)
5-Trifluorothymine
Trifluorothymine 5-
ifluoromethyl)pyrimidine-2,4(1H,3H)-dione
Trifluorothymine-13C4-15N2
Trifluorothymine,54-20-6
5-(Trifluoromethyl)pyrimidine-2,4(1H,3H)-dione
5-(TRIFLUOROMETHYL)URACIL
TRIFLUOROMETHYLURACIL
5-(trifluoroMethyl)pyriMidine-2,4-diol
5-Trifluoromethyl
2,4-DIHYDROXY-5-TRIFLUOROMETHYL-1H-PYRIMIDINE
5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione (5-(trifluoromethyl)uracil
5-TRIFLUOROMETHYLURACIL
Trifluorothymine
54-20-6
Pyrimidines
Heterocyclic Building Blocks
Building Blocks
Pyrimidine
Pyrimidines
Miscellaneous
Pyrimidine series
Indolines ,Indoles ,Indazoles
54-20-6