ChemicalBook >> CAS DataBase List >>Biotin-PEG12-NHS ester
Biotin-PEG12-NHS ester
- CAS No.
- 1934296-88-4
- Chemical Name:
- Biotin-PEG12-NHS ester
- Synonyms
- 2，5-Dioxopyrrolidin-1-yl 41-oxo-45-((3aS，4S，6aR)-2-oxohexahydro-1H-thieno[3，4-d]imidazol-4-yl)-4，7，10，13，16，19，22，25，28，31，34，37-dodecaoxa-40-azapentatetracontan-1-oate;4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxa-40-azapentatetracontanoic acid, 45-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-41-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
- CBNumber:
- CB88054670
- Molecular Formula:
- C41H72N4O18S
- Molecular Weight:
- 941.09
- MDL Number:
- MOL File:
- 1934296-88-4.mol
Last updated:2023-04-23 13:52:06
Biotin-PEG12-NHS ester Chemical Properties,Uses,Production
Biological Activity
Biotin-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Biotin-PEG12-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
Biotin-PEG12-NHS ester Suppliers
Global( 17)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503259 +86-19930503259 | cherry@crovellbio.com | China | 18443 | 58 |
| Chengdu Pukang Biotechnology Co., Ltd | 028-82550498 19102685862 | sales@pu-kang.com | China | 485 | 58 |
| TargetMol Chemicals Inc. | 021-021-33632979 15002134094 | marketing@targetmol.com | China | 7854 | 58 |
| Hunan HuaTeng Pharmaceutical Co., Ltd., | 400-8592883 15367835770 | viola@huatengsci.com | China | 5877 | 58 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3500 | 55 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12308 | 58 |
| Hangzhou HanLai Biochemical Technology Co., Ltd. | 0571-86101219 13675881727 | sales@leobiochem.com | China | 433 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 39997 | 58 |
| Xi'an Qiyue Biotechnology Co., Ltd. | 400-400-6966-012-012 17778955912 | 2957605606@qq.com | China | 2535 | 58 |
4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxa-40-azapentatetracontanoic acid, 45-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-41-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
2，5-Dioxopyrrolidin-1-yl 41-oxo-45-((3aS，4S，6aR)-2-oxohexahydro-1H-thieno[3，4-d]imidazol-4-yl)-4，7，10，13，16，19，22，25，28，31，34，37-dodecaoxa-40-azapentatetracontan-1-oate
1934296-88-4
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