3-nitro-4-hydroxypropiophenone

CAS No.
50916-44-4
Chemical Name:
3-nitro-4-hydroxypropiophenone
Synonyms
3-nitro-4-hydroxypropiophenone;4'-Hydroxy-3'-nitropropiophenone;1-(4-hydroxy-3-nitrophenyl)propan-1-one;1-Propanone, 1-(4-hydroxy-3-nitrophenyl)-
CBNumber:
CB8947149
Molecular Formula:
C9H9NO4
Molecular Weight:
195.17
MDL Number:
MFCD14552665
MOL File:
50916-44-4.mol

3-nitro-4-hydroxypropiophenone Properties

Melting point 65.4–66.2°C
Boiling point 296.8±20.0 °C(Predicted)
Density 1.321±0.06 g/cm3(Predicted)
pka 5.33±0.35(Predicted)

3-nitro-4-hydroxypropiophenone Chemical Properties,Uses,Production

Preparation

Preparation by treatment of 4-hydroxypropiophenone with fuming nitric acid or with nitric acid in concentrated sulfuric acid between ?2° and 0° (80%)
Preparation by Friedel–Crafts acylation of o-nitrophenol with propionyl chloride in nitrobenzene in the presence of aluminium chloride at 55–60° for 2.5 h, then at r.t. overnight
Also obtained (poor yield) by Fries rearrangement of 2-nitrophenyl propionate in nitrobenzene with aluminium chloride at 90° for 8 h, then at r.t. overnight
Also obtained by reaction of concentrated nitric acid with 2,2′-dihydroxy-5, 5′-dipropionyldiphenyl sulfide (m.p. 103°) in concentrated sulfuric acid at r.t. overnight.

3-nitro-4-hydroxypropiophenone Preparation Products And Raw materials

Raw materials

Preparation Products

3-nitro-4-hydroxypropiophenone Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
Eurolabs Limited -- United Kingdom 6323 46
HONEST JOY HOLDINGS LIMITED -- sales@honestjoy.cn United States 6702 54
Service Chemical Inc. -- sales@chemos-group.com Germany 6373 71
ecochem international chemical broker -- export@ecochem.dk Europe 6385 66
kemikalieimport -- Sales@kemikalieimport.dk Europe 6699 47
Changzhou Keylab Chemical Co., Ltd -- China 436 61

50916-44-4(3-nitro-4-hydroxypropiophenone )Related Search:

1-(4-hydroxy-3-nitrophenyl)propan-1-one 3-nitro-4-hydroxypropiophenone 4'-Hydroxy-3'-nitropropiophenone 1-Propanone, 1-(4-hydroxy-3-nitrophenyl)- 50916-44-4