ChemicalBook >> CAS DataBase List >>PVM/MA
PVM/MA
- CAS No.
- 1644545-52-7
- Chemical Name:
- PVM/MA
- Synonyms
- AG881;E7386;AG081;HS-01;PVM/MA;AG-881;E-7386;s-22611;FF10101;CS-2621
- CBNumber:
- CB91403717
- Molecular Formula:
- C14H13ClF6N6
- Molecular Weight:
- 414.74
- MDL Number:
- MFCD31630835
- MOL File:
- 1644545-52-7.mol
Last updated:2024-03-14 13:28:14
| Boiling point | 467.5±55.0 °C(Predicted) |
|---|---|
| Density | 1.491±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml |
| form | A crystalline solid |
| pka | 1.49±0.41(Predicted) |
| FDA UNII | 789Q85GA8P |
| NCI Drug Dictionary | vorasidenib |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
PVM/MA price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28462 | Vorasidenib | 1644545-52-7 | 1mg | $110 | 2024-03-01 | Buy |
| Cayman Chemical | 28462 | Vorasidenib | 1644545-52-7 | 10mg | $757 | 2024-03-01 | Buy |
| Cayman Chemical | 28462 | Vorasidenib | 1644545-52-7 | 5mg | $433 | 2024-03-01 | Buy |
| ChemScene | CS-8033 | Vorasidenib 99.87% | 1644545-52-7 | 5mg | $150 | 2021-12-16 | Buy |
| ChemScene | CS-8033 | Vorasidenib 99.87% | 1644545-52-7 | 10mg | $250 | 2021-12-16 | Buy |
PVM/MA Chemical Properties,Uses,Production
Uses
PF-06291874 is a novel and potent glucagon receptor antagonist for the potential treatment of diabetes mellitus. PF-06291874, has a lower molcular weight and lipophilicity than historical glucagon receptor antagonists, resulting in excellent selectivity in broad-panel screening, lower cytotoxicity, and excellent overall in vivo safety in early pre-clinical testing.
Synthesis
Maleic anhydride (MA) was added to a solvent mixture of cyclohexane and ethyl acetate in a polymerizer equipped with an agitator, a reflux condenser, and an inner temperature-controlling device. The polymerizer was purged of air and filled with nitrogen. The solution was heated to 70 °C, and then an initiator solution (lauroyl peroxide dissolved in ethyl acetate) and Methyl vinyl ether (MVE) were added to the polymerizer in a dropwise manner. A slurry was obtained, which was filtered and dried under a vacuum to obtain a white powdery copolymer.
PVM/MA Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 92)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Wuhan Nutra Biotechnology Co.,Ltd | +8617786394783 | nutrabiotech@outlook.com | China | 300 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
Related articles
- The brief introduction of PVM/MA
- The copolymer of MVE and maleic anhydride (MA) is most widely used.
- Mar 14，2024
View Lastest Price from PVM/MA manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-10-08 | Vorasidenib;AG-881
1644545-52-7
|
US $0.00-0.00 / g | 1g | 98% | 100kgs | Wuhan Nutra Biotechnology Co.,Ltd |
-
- Vorasidenib;AG-881
1644545-52-7
- US $0.00-0.00 / g
- 98%
- Wuhan Nutra Biotechnology Co.,Ltd
1644545-52-7(PVM/MA)Related Search:
PF06291874
Vorasidenib
PVM/MA
S-N-NITROSO-2-METHYLPIPERIDINE
PCB138/160
FLEABUSTERSRXPOWDER
15-HYDROPEROXYEICOSATETRAENOICACID
CALCIUM(C10-C16)ALKYLBENZENESULPHONATE
(5Z,8Z,11Z,14Z)-15-Hydroperoxy-5,8,11,14-icosatetraenoic acid
(5Z,8Z,11Z,14Z)-15-Hydroperoxyicosa-5,8,11,14-tetraenoic acid
15-HPETE
AG881
AG-881
4-(2-acetyl-5-chlorophenyl)-5-methoxypyridin-2(1H)-one
E7386
E-7386
s-22611
FM381 FM-381
6-(6-chloropyridin-2-yl)-N2,N4-bis((R)-1,1,1-trifluoropropan-2-yl)-1,3,5-triazine-2,4-diamine
Amino Carboxyl Magnetic Beads
AG081
FF10101
FF-10101
benzyl ester of L-carnitine
CS-2621
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3-bromo-5-bromoacetyl salicylamide
(R)-1-(3-(3-amino-6-(2-fluoro-5-isopropoxyphenyl)pyrazine-2-carboxamido)pyridin-4-yl)piperidine-3-carboxylic acid?
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Vorasidenib (AG881)
Trichloroethyl 2-(Bromomethyl)-2-hydroxyhehahydrofuro(3,2-b)pyridine-4(2H)-carboxylate
2-[3-(2H-indazol-3-ylmethyl)-2,4-dioxo-5-phenyl-1,5-benzodiazepin-1-yl]-N-(4-methoxyphenyl)-N-propan-2-ylacetamide
2,2'-(propane-2,2- diylbis(sulfanediyl))bis(ethan-1-ol)
(E)-Ethyl Docos-2-Enoate
HS-01
1,3,5-Triazine-2,4-diamine, 6-(6-chloro-2-pyridinyl)-N2,N4-bis[(1R)-2,2,2-trifluoro-1-methylethyl]-
2-[1-(2-Hydroxy-ethylsulfanyl)-1-methyl-ethylsulfanyl]-ethanol
4-N-(2,4-dimethoxyphenyl)-6-N-(4-(4-methylpiperazin-1-yl)phenyl)pyrimidine-4,6-diamine, N4-(2,4-dimethoxyphenyl)-N6-(4-(4-methylpiperazin-1-yl)phenyl)pyrimidine-4,6-diamine
IMB-XH1
2-chloro-N1,N4-bis(4-cyanophenyl)terephthalamide
(+)-Quassin
high quality 3-aminophenylacetylene HCL
Sodium 2,3,3,3-Tetrafluoro-2-(1,1,2,2,2-Pentafluoroethoxy)propanoate
2‐{2‐[2‐(2,2‐difluoroethoxy)ethoxy]ethoxy}‐1,1‐difluoroethane
4-hydrazineylnicotinamide
inhibit,AG 881,Vorasidenib,AG881,Inhibitor,Isocitrate Dehydrogenase (IDH)
SRD5A1-IN-1
AKR1C3-IN-9
ARUK2001607
TLC Plates,Silca Gel 60 F254 Aluminium Plating
2-(1-ethoxyvinyl)-4,4,5,5-tetraethyl-1,3,2-dioxaborolane
(S)-1-amino-1-(5-bromo-2-fluorophenyl)ethan-1-ol
N-Difluoromethyltriazolyl-4-carboxamide
N-Trifluoromethyltriazolyl-4-carboxamide
4-Cyano-1-(perfluoroethoxy)pyridin-1-ium bis((trifluoromethyl)sulfonyl)amide
Sodium 2-azido-2,2-difluoroacetate
(1-(2,2,3,3-Tetrafluoropropyl)-1H-1,2,3-triazol-4-yl)methanaminium chloride
1-Difluoroethyltriazolyl-4-methylamine hydrochloride