Pranoprofen
- CAS No.
- 52549-17-4
- Chemical Name:
- Pranoprofen
- Synonyms
- 2-(5H-Chromeno[2,3-b]pyridin-7-yl)propanoic acid;Niflan;Y 8004;Cesflan;Oftalar;ranoprofen;PRANOPROFEN;pyranoprofen;dl-Pranoprofen;(RS)-Pranoprofen
- CBNumber:
- CB9189564
- Molecular Formula:
- C15H13NO3
- Molecular Weight:
- 255.27
- MDL Number:
- MFCD00866111
- MOL File:
- 52549-17-4.mol
- MSDS File:
- SDS
Melting point | 182-183° |
---|---|
Boiling point | 398.5°C (rough estimate) |
Density | 1.1654 (rough estimate) |
refractive index | 1.5500 (estimate) |
storage temp. | 2-8°C |
solubility | DMSO (Slightly), Methanol (Slightly) |
pka | 4.27±0.10(Predicted) |
form | powder |
color | white to beige |
CAS DataBase Reference | 52549-17-4(CAS DataBase Reference) |
FDA UNII | 2R7O1ET613 |
ATC code | S01BC09 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H301 | |||||||||
Precautionary statements | P301+P310+P330 | |||||||||
RIDADR | UN 2811 6.1 / PGIII | |||||||||
RTECS | DJ3100950 | |||||||||
Toxicity | LD50 in male mice, rats (mg/kg): 447.3, 87.3 orally (Edanaga) | |||||||||
NFPA 704 |
|
Pranoprofen price More Price(35)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SML1423 | Pranoprofen ≥98% (HPLC) | 52549-17-4 | 50mg | $38.9 | 2024-03-01 | Buy |
Sigma-Aldrich | SML1423 | Pranoprofen ≥98% (HPLC) | 52549-17-4 | 250mg | $115 | 2024-03-01 | Buy |
Cayman Chemical | 17875 | Pranoprofen ≥98% | 52549-17-4 | 50mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 17875 | Pranoprofen ≥98% | 52549-17-4 | 1g | $359 | 2024-03-01 | Buy |
Cayman Chemical | 17875 | Pranoprofen ≥98% | 52549-17-4 | 100mg | $61 | 2024-03-01 | Buy |
Pranoprofen Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Originator
Niflan, Yoshitomi ,Japan ,1981
Uses
Pranoprofen is an anti-inflammatory used in ophthalmology.
Definition
ChEBI: Pranoprofen is a pyridochromene.
Manufacturing Process
A mixture of 100 g of ethyl 2-cyano-2-(5H-[1]benzopyrano[2,3-b]-pyridin-7yl)propionate, 500 ml of glacial acetic acid and 200 g of concentrated hydrochloric acid is refluxed for 48 hours. The reaction mixture is concentrated, and the residue is dissolved in hot water. The solution is adjusted to pH 2 to 3 by addition of 10% sodium hydroxide. The resulting crystalline precipitate is washed thoroughly with water, and recrystallized from aqueous dioxane to give 74 g of 2-(5H-[1]benzopyrano[2,3-b]-pyridin-7yl)propionic acid as white crystals melting at 183°C to 183.5°C.
Therapeutic Function
Analgesic, Antiinflammatory
General Description
Pranoprofen is an arylalkanoic acid and a non-steroidal anti-inflammatory drug.
Biochem/physiol Actions
Pranoprofen is used in eyes to treat chronic allergic conjunctivitis. It is also used as an anti-inflammatory and analgesic drug after strabismus surgery.
Pranoprofen Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shaanxi Dideu Medichem Co. Ltd | 18192627656 | 1012@dideu.com | China | 3002 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12465 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5895 | 58 |
airuikechemical co., ltd. | +undefined86-15315557071 | sales02@sdzhonghuimaterial.com | China | 983 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21666 | 55 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8820 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
View Lastest Price from Pranoprofen manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-23 | Pranoprofen
52549-17-4
|
US $1.90 / KG | 1KG | 99% | 10 ton | Hebei Chuanghai Biotechnology Co,.LTD | ||
2024-09-23 | Pranoprofen
52549-17-4
|
US $0.00-0.00 / g | 1g | 99.9% | 20 tons | airuikechemical co., ltd. | ||
2024-09-12 | Pranoprofen
52549-17-4
|
US $1.00-22.00 / KG | 1KG | 99% | 100000KG | Shaanxi Dideu Medichem Co. Ltd |
- Pranoprofen
52549-17-4
- US $1.90 / KG
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
- Pranoprofen
52549-17-4
- US $0.00-0.00 / g
- 99.9%
- airuikechemical co., ltd.
- Pranoprofen
52549-17-4
- US $1.00-22.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
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