ChemicalBook >> CAS DataBase List >>5-Hydroxyindole-2-carboxylic acid

5-Hydroxyindole-2-carboxylic acid

CAS No.
21598-06-1
Chemical Name:
5-Hydroxyindole-2-carboxylic acid
Synonyms
5-HO-ICA;NSC 117338;5-HYDROXY-2-INDOLECARBOXYLIC ACID;5-HYDROXYINDOLE-2-CARBOXYLIC ACID;5-Hydroxyindole-2-carboxylicacid,97%;5-Hydroxy-2-indolecarboxylic acid 98%;5-HYDROXY-1H-INDOLE-2-CARBOXYLIC ACID;5-Hydroxyindole-2-carboxylic acid 98%;5-Hydroxy-2-indolecarboxylic acid,98%;1H-Indole-2-carboxylic acid, 5-hydroxy-
CBNumber:
CB9206982
Molecular Formula:
C9H7NO3
Molecular Weight:
177.16
MDL Number:
MFCD00005615
MOL File:
21598-06-1.mol
MSDS File:
SDS
Last updated:2023-05-04 17:34:35

5-Hydroxyindole-2-carboxylic acid Properties

Melting point 249 °C (dec.) (lit.)
Boiling point 309.06°C (rough estimate)
Density 1.3312 (rough estimate)
refractive index 1.5200 (estimate)
storage temp. Sealed in dry,2-8°C
solubility chloroform/ethanol (1:1): soluble50mg/mL, clear to slightly hazy, yellow to brown
pka 4.38±0.30(Predicted)
form Fuming Liquid
color Clear colorless to slightly yellow
BRN 153214
CAS DataBase Reference 21598-06-1(CAS DataBase Reference)
FDA UNII 5XP5R85YFD

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-21/22
Safety Statements  26-36-36/37/39
WGK Germany  3
HS Code  29339900
NFPA 704
1
2 1

5-Hydroxyindole-2-carboxylic acid price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 143510 5-Hydroxyindole-2-carboxylic acid 98% 21598-06-1 1g $105 2024-03-01 Buy
Sigma-Aldrich 143510 5-Hydroxyindole-2-carboxylic acid 98% 21598-06-1 5g $177.6 2024-03-01 Buy
Alfa Aesar L00786 5-Hydroxyindole-2-carboxylic acid, 97% 21598-06-1 1g $61.65 2024-03-01 Buy
Alfa Aesar L00786 5-Hydroxyindole-2-carboxylic acid, 97% 21598-06-1 5g $243 2024-03-01 Buy
Usbiological 161918 5-Hydroxyindole-2-carboxylic Acid 21598-06-1 2.5g $425 2021-12-16 Buy
Product number Packaging Price Buy
143510 1g $105 Buy
143510 5g $177.6 Buy
L00786 1g $61.65 Buy
L00786 5g $243 Buy
161918 2.5g $425 Buy

5-Hydroxyindole-2-carboxylic acid Chemical Properties,Uses,Production

Chemical Properties

light yellow to beige crystalline powder

Uses

5-Hydroxyindole-2-carboxylic acid was used in HPLC-amperometric detection of serotonin in plasma, platelets and urine.

Uses

• ;Reactant for preparation of indole C5-O-substituted seco-cyclopropylindole analogs as potential anticancer agents• ;Reactant for microwave combinatorial synthesis of indolic arylpiperazine derivatives as ligands for 5-HT1A, 5-HT2A, and 5-HT2C receptors1• ;Reactant for preparation of melanins as novel nature-inspired radioprotectors2• ;Reactant for preparation of 5-Hydroxyindole-2-carboxylic acid amides as histamine-3 receptor inverse agonists for the treatment of obesity3• ;Reactant for preparation of conformationally constrained peptidomimetic inhibitors of signal

Uses

A competitive antagonist of potentiation by glycine at the N-methyl-D-aspartate receptors that have been linked to neuronal death, assiciated to such afflictions as stroke and epilepsy.

Definition

ChEBI: 5-Hydroxyindole-2-carboxylic acid is an indolyl carboxylic acid.

General Description

5-Hydroxyindole-2-carboxylic acid on oxidation with KMnO4 yields pyrrole-2,3,5-tricarboxylic acid.

5-Hydroxyindole-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 142)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47464 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29827 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196 sale04@alfachem.cn China 12337 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17368 58
KARMEL TECHNOLOGY (HK) CO.,LIMITED
+8618795957998 karmelhk@126.com CHINA 2886 58
Unipharm pharmaceutical industry Co., Ltd
536-8266195 +8613953676784 lee@unipharm-sd.com China 1206 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com CHINA 52867 58

View Lastest Price from 5-Hydroxyindole-2-carboxylic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Hydroxyindole-2-carboxylic acid pictures 2020-01-03 5-Hydroxyindole-2-carboxylic acid
21598-06-1
US $6.60 / KG 1KG 97%-99% 1kg -1000kg Career Henan Chemical Co
5-HYDROXYINDOLE-2-CARBOXYLIC ACID 5-HYDROXY-1H-INDOLE-2-CARBOXYLIC ACID 5-HYDROXY-2-INDOLECARBOXYLIC ACID 5-HO-ICA 5-Hydroxyindole-2-carboxylicacid,97% 5-Hydroxy-2-indolecarboxylic acid, 98% 1GR NSC 117338 5-Hydroxy-2-indolecarboxylic acid 98% 5-HYDROXYINDOLE-2-CARBOXYLIC ACID(5OHI2CA) 5-Hydroxy-2-indolecarboxylic acid,98% 5-Hydroxyindole-2-carboxylic acid 98% 1H-Indole-2-carboxylic acid, 5-hydroxy- 21598-06-1 C9H7NO3 Building Blocks Heterocyclic Building Blocks Indoles Building Blocks Heterocyclic Building Blocks Building Blocks C7 to C9 Chemical Synthesis Heterocyclic Building Blocks Indoles Heterocyclic Compounds Indoles and derivatives Indole Organic acids