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EPA

CAS No.
10417-94-4
Chemical Name:
EPA
Synonyms
EICOSAPENTAENOIC ACID;CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID;ICOSAPENT;TIMNODONIC ACID;Eicosapentaenoic;5C,8C,11C,14C,17C-EICOSAPENTAENOIC ACID;Eicosapentaenoic acid (EPA);5,8,11,14,17-EICOSAPENTAENOIC ACID;EPA;92-PGM
CBNumber:
CB9426441
Molecular Formula:
C20H30O2
Molecular Weight:
302.45
MDL Number:
MFCD00065716
MOL File:
10417-94-4.mol
MSDS File:
SDS
Last updated:2024-04-07 18:44:46

EPA Properties

Melting point −54-−53 °C(lit.)
Boiling point 439℃
Density 0.943 g/mL at 25 °C(lit.)
refractive index n20/D 1.4977(lit.)
Flash point 93 °C
storage temp. -20°C
solubility Soluble in methanol
pka 4.75±0.10(Predicted)
form liquid
color Colorless to pale yellow
Sensitive Air & Light Sensitive
Merck 14,3531
BRN 1714433
Stability Stable for 1 year as supplied (unopened). After opening, EPA must be stored under inert gas at -80°C. Solutions in DMSO or ethanol should also be stored under inert gas and may be kept at -80°C for up to 2 months.
InChIKey RRGOKSYVAZDNKR-ARJAWSKDSA-N
LogP 6.232 (est)
FDA UNII AAN7QOV9EA

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P305+P351+P338
Hazard Codes  C
Risk Statements  34
Safety Statements  26-36/37/39-45
RIDADR  UN 3265 8/PG 3
WGK Germany  3
8-10-23
HazardClass  8
HS Code  29161900
NFPA 704
3
3 0

EPA price More Price(51)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 44864 cis-5,8,11,14,17-Eicosapentaenoic acid analytical standard 10417-94-4 100mg $193 2024-03-01 Buy
Sigma-Aldrich 44864 cis-5,8,11,14,17-Eicosapentaenoic acid analytical standard 10417-94-4 500mg $756 2024-03-01 Buy
Sigma-Aldrich E-113 cis-5,8,11,14,17-Eicosapentaenoic acid 500?μg/mLinethanol,certifiedreferencematerial,Cerilliant? 10417-94-4 1mL $113 2022-05-15 Buy
TCI Chemical E0441 all cis-5,8,11,14,17-Eicosapentaenoic Acid >95.0%(GC) 10417-94-4 100mg $248 2024-03-01 Buy
TCI Chemical E0441 all cis-5,8,11,14,17-Eicosapentaenoic Acid >95.0%(GC) 10417-94-4 500mg $739 2024-03-01 Buy
Product number Packaging Price Buy
44864 100mg $193 Buy
44864 500mg $756 Buy
E-113 1mL $113 Buy
E0441 100mg $248 Buy
E0441 500mg $739 Buy

EPA Chemical Properties,Uses,Production

Description

EPA is an ω-3 fatty acid abundantly available in marine organisms. It is oxygenated by COX-1 and COX-2 at rates of about 5% and 30%, respectively, compared to arachidonic acid. EPA has been shown to offer protection against coronary heart disease, thrombosis, ischemic brain injury, scaly dermatitis, and some inflammatory diseases.

Chemical Properties

Colorless Oil

Uses

cis-5,8,11,14,17-Eicosapentaenoic acid has been used an analytical standard for the synthesis followed by investigation of pharmacological properties of aconitine-derived lipo-alkaloids.

Uses

cis-5,8,11,14,17-Eicosapentaenoic acid has been used:

  • to test pharmacologic effect on steatosis in hepatocytes
  • as an analytical standard in Raman spectra measurements to characterize human breast cancer samples
  • in lipid peroxidation assay in mouse embryonic fibroblasts and in pre-treatment of cells for cell viability studies

Uses

Important polyunsaturated fatty acid of the marine food chain that serves as a precursor for the prostaglandin-3 and thromboxane-3 families. It differs from arachidonic acid (the eicosatetraenoic acid that is a precursor for the prostaglandin and thromboxane-2 families) by the extra double bond between the third and fourth carbons from the “methyl end” of the molecule. Antilipemic.

Definition

ChEBI: An icosapentaenoic acid having five cis-double bonds at positions 5, 8, 11, 14 and 17.

brand name

Decabid (Lilly).

General Description

Eicosapentaenoic acid (cis-5,8,11,14,17), also known as EPA, is a long-chain omega-3 fatty acid. Studies suggests that EPA as well as other fatty acids can serve as biomarkers for cardiovascular disease, and nutritional and metabolic disorders. This certified solution standard is suitable for use as starting material in the preparation of linearity standards, calibrators, or controls in mass spectrometry-based EPA testing applications such as assessment of cardiovascular?disease risk and fatty acid deficiency, and detection and quantification of EPA in nutraceuticals and dietary supplements.

Biochem/physiol Actions

5-Lipoxygenase inhibitor; reduces thromboxane A2 production.

References

1) Lee et al. (1985), Effect of dietary enrichment with eicosapentaenoic and docosahexaenoic acids on in vitro neutrophil and monocyte leukotriene generation and neutrophil function; N. Engl. J. Med., 312 1217 2) Nicholson et al. (2013), The role of marine n-3 fatty acids in improving cardiovascular health: a review; Food Funct., 4 357

86227-47-6
10417-94-4
Synthesis of EPA from Ethyl all cis-5,8,11,14,17-Eicosapentaenoate
Global( 318)Suppliers
Supplier Tel Email Country ProdList Advantage
Xi'an Kono chem co., Ltd.,
029-86107037 13289246953 info@konochemical.com China 2995 58
TCI Europe
320-37350700 sales@tcieurope.eu Europe 23680 75
Nantong Guangyuan Chemicl Co,Ltd
+undefined17712220823 admin@guyunchem.com China 616 58
airuikechemical co., ltd.
+undefined86-15315557071 sales02@airuikechemical.com China 994 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15928 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58

View Lastest Price from EPA manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Eicosapentaenoic Acid pictures 2024-04-07 Eicosapentaenoic Acid
10417-94-4
US $0.00-0.00 / g 1g 99.9% 20 tons airuikechemical co., ltd.
Eicosapentaenoic Acid pictures 2024-03-08 Eicosapentaenoic Acid
10417-94-4
US $10.00 / kg 1kg 99% 1000kg Nantong Guangyuan Chemicl Co,Ltd
Eicosapentaenoic acid EPA 10417-94-4 pictures 2022-02-14 Eicosapentaenoic acid EPA 10417-94-4
10417-94-4
US $20.00 / g 1g ≥98% 1000.00 kgs NanJing Spring & Autumn Biological Engineering CO., LTD.
C20:5 (ALL CIS-5,8,11,14,17) ACID C20:5 OMEGA-3 EICOSA-5Z,8Z,11Z,14Z,17Z-PENTAENOIC ACID EICOSAPENTAENOIC CID EPA EPA 5C,8C,11C,14C,17C 5Z,8Z,11Z,14Z,17Z-EICOSAPENTAENOIC ACID ALL CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID ALL CIS-5,8,11,14,17-ICOSAPENTAENOIC ACID ALL CIS 5-8-11-14-17 EPA (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic Acid CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID*F REE ACID AP 5,8,11,14,17-EICOSAPENTAENOIC ACID, STAN DARD FOR GC CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID, 90+% 5,8,11,14,17-Eicosapentaenoic acid, (5Z,8Z,11Z,14Z,17Z)- (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic acid eiosapentaenoic acid,EPA 5,8,11,14, acid 5, EPA / DHA 40% EPA 18 / DHA 12 EPA 18 / DHA 12 DEODORIZED SEA OIL POWDER 30 EPA 18 / DHA 12 Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3) Single-Use Eicosapentaenoic Acid (peroxide free) CIS-5,8,11,14,17-EICOSAPENTAENOIC AC (all-Z)-5,8,11,14,17-Eicosapentaenoic Acid EPA 45G Icosapentaenoic Acid Incromega E 7010SR Ropufa 70 5,8,11,14,17-eicosapentaenoic acid: EPA (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Icosapentaenoic acid 92-PGM 5,8,11,14,17-Eicosapentaenoic acid (all-cis) EICOSAPENTAENOIC ACID(EPA)(SG) cis-5,8,11,14,17-Eicosapentaenoic acid ,95% cis-5,8,11,14,17-Eicosapentaenoic acid ,70% cis-5,8,11,14,17-Eicosapentaenoic acid,EPA, Timnodonic acid Eicosapentaenoic Acid (peroxide free) EPA (Eicosapentaenoic Acid) EPA, Timnodonic acid EPA all cis-5,8,11,14,17-Icosapentaenoic Acid Eicosapentaenoic acid (EPA) -d5 cis-5,8,11,14,17-Dicosapentaenoic acid (2E,4E,6E,8E,10E)-icosa-2,4,6,8,10-pentaenoic acid Eicosapentaenoic acid-(5,8,11,14,17) TIMNODONIC ACID(EPA) cis-4,7,10,13,16,19-Docosapentaenoic Solution, 100ppm Eicosapentaenoic acid EPA 10417-94-4 cis-5,8,11,14,17-Eicosapentaenoic Acid(Epa-M)(C20:5) Eicosapentaenoic Acid Powder allcis-5,8,11,14,17-EicosapentaenoicAcid> cis-5,8,11,14,17-Eicosapentaenoic acid Solution in Hexane, 100μg/mL all-cis-5,8,11,14,17-icosapentaenoicaci "cis-Eicosapenta-5, 8, 11, 14, 17-enoic acid D5" Eicosapentaenoic AcidQ: What is Eicosapentaenoic Acid Q: What is the CAS Number of Eicosapentaenoic Acid Q: What is the storage condition of Eicosapentaenoic Acid Q: What are the applications of Eicosapentaenoic Acid EPA free acid