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Angeli’s Salt

CAS No.
13826-64-7
Chemical Name:
Angeli’s Salt
Synonyms
AS;Angeli Salt;ANGELI'S SALT;Sodium hyponitrate;Sodium oxyhyponitrite;SODIUM TRIOXODINITRATE;SODIUM ALPHA-OXYHYPONITRITE;CUVSFFFYSKZMEE-UHFFFAOYSA-N;HYPONITRIC ACID DISODIUM SALT;Sodium N-nitrohydroxylaminate
CBNumber:
CB9219704
Molecular Formula:
N2Na3O3+
Molecular Weight:
144.98
MDL Number:
MFCD33404171
MOL File:
13826-64-7.mol
MSDS File:
SDS
Last updated:2023-05-21 10:59:17

Angeli’s Salt Properties

Density 2.26 (monohydrate)
storage temp. Store at -20°C
solubility H20: 50 mg/ml; PBS (pH 7.2): 50 mg/ml
form A crystalline solid
FDA UNII S8LUE47R4Z

Angeli’s Salt price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 176695 Angeli’s Salt - CAS 13826-64-7 - Calbiochem 13826-64-7 10mg $125 2024-03-01 Buy
Cayman Chemical 82230 Angeli’s Salt ≥99% 13826-64-7 5mg $30 2024-03-01 Buy
Cayman Chemical 82230 Angeli’s Salt ≥99% 13826-64-7 10mg $56 2024-03-01 Buy
Cayman Chemical 82230 Angeli’s Salt ≥99% 13826-64-7 50mg $225 2024-03-01 Buy
Cayman Chemical 82230 Angeli’s Salt ≥99% 13826-64-7 100mg $392 2024-03-01 Buy
Product number Packaging Price Buy
176695 10mg $125 Buy
82230 5mg $30 Buy
82230 10mg $56 Buy
82230 50mg $225 Buy
82230 100mg $392 Buy

Angeli’s Salt Chemical Properties,Uses,Production

Description

The chemical feat that perhaps best illustrates Angeli's intuitive talent was the discovery more than a century ago of the sodium salt of nitroxylaminic acid, also called Angeli's Salt (Na2N2O3). Na2[ON=NO2] is regarded as a classic nitroxyl(N=O-) donor, but under certain conditions evolution of NO is also observed. Angelo Angeli found that'salts of nitroxylaminic acid are readily resolved into the corresponding nitrites and the unsaturated nitroxyl residue. Angeli suggested their use as possible in vitro and in vivo sources of HNO,but physiological properties of this molecule didn't attract very much attention until the end of the 20th century.
Angeli's salt can be conveniently synthesized by treating hydroxylamine hydrochloride with excess sodium hydroxide,yielding hydroxylamine,which is further treated with butyl nitrate to produce the salt as a white solid.

Uses

Sodium Oxyhyponitrite is used in the treatment for hemolysis.

Uses

HNO/NO- donor in biochemical model studies.

General Description

A nitroxyl anion (NO) donor that spontaneously dissociates in a pH dependent first order process to liberate 0.54 moles of NO per mole of the parent compound. Half-life (t?) in 100 mM phosphate buffer, pH 7.4 is 2.3 minutes at 37°C. Decomposition is nearly instantaneous at pH 5.0.

Biochem/physiol Actions

Primary TargetNitroxyl anion (NO-) donor

Angeli’s Salt Preparation Products And Raw materials

Raw materials

Preparation Products

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ANGELI'S SALT AS HYPONITRIC ACID DISODIUM SALT DISODIUM DIAZEN-1-IUM-1,2,2-TRIOLATE SODIUM TRIOXODINITRATE SODIUM ALPHA-OXYHYPONITRITE Sodium oxyhyponitrite Sodium N-nitrohydroxylaminate Sodium hyponitrate CUVSFFFYSKZMEE-UHFFFAOYSA-N Angeli Salt 13826-64-7 N2Na3O3 Na2N2O3