ChemicalBook >> CAS DataBase List >>VU 0357017 hydrochloride
VU 0357017 hydrochloride
- CAS No.
- 1135242-13-5
- Chemical Name:
- VU 0357017 hydrochloride
- Synonyms
- CS-2319;VU0357017;CID 25010775;SID 56353039;VU0357017 HCI;ML071 hydrochloride;VU 0357017 hydrochloride;VU0357017 monohydrochloride;Ethyl 4-(2-(2-methylbenzamido)ethylamino)piperidine-1-carboxylate hydrochloride;VU0-357017;VU 0357017;CID-25010775; VU-0357017 HYDROCHLORIDE; VU 0357017 HYDROCHLORIDE
- CBNumber:
- CB92546794
- Molecular Formula:
- C18H28ClN3O3
- Molecular Weight:
- 369.9
- MDL Number:
- MFCD17215959
- MOL File:
- 1135242-13-5.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
VU 0357017 hydrochloride price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | V4640 | VU0357017 monohydrochloride ≥98% (HPLC) | 1135242-13-5 | 5mg | $134 | 2024-03-01 | Buy |
| Sigma-Aldrich | V4640 | VU0357017 monohydrochloride ≥98% (HPLC) | 1135242-13-5 | 25mg | $465 | 2022-05-15 | Buy |
| Cayman Chemical | 11939 | VU0357017 (hydrochloride) ≥98% | 1135242-13-5 | 1mg | $33 | 2024-03-01 | Buy |
| Cayman Chemical | 11939 | VU0357017 (hydrochloride) ≥98% | 1135242-13-5 | 5mg | $90 | 2024-03-01 | Buy |
| Cayman Chemical | 11939 | VU0357017 (hydrochloride) ≥98% | 1135242-13-5 | 10mg | $164 | 2024-03-01 | Buy |
VU 0357017 hydrochloride Chemical Properties,Uses,Production
Uses
VU0357017 is a subtype-selective M1 muscarinic acetylcholine allosteric agonist. VU0357017 has a potency of 200 nM and Achmax of 81% and had no activity at M2-M5 up to the highest concentrations tested and also had little or no detectable antagonist activity at any other mAChR subtype at concentrations over 2 orders of magnitude higher than those required to activate M1 or activity at a large panel of GPCRs, ion channels, and transporters. In contrast, TBPB inhibited responses to ACh at each of the other mAChR subtypes. VU0357017 was active in reversing cognitive deficits induced by Scopolamine (S200000) in a preclinical rodent model.
Uses
VU 0357017 Hydrochloride is a cholinergic M1 receptor antagonist and a cholinomimetic agent used for the treatment of behavioral and/or mental disorders.
storage
+4°C
VU 0357017 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 58)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| VDM Biochemicals | 0330-2528181 | sales@vdmbio.com | United States | 510 | 64 |
| Supplier | Advantage |
|---|---|
| ATK CHEMICAL COMPANY LIMITED | 60 |
| BOC Sciences | 58 |
| Career Henan Chemica Co | 58 |
| InvivoChem | 58 |
| TargetMol Chemicals Inc. | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 58 |
| Aladdin Scientific | 58 |
| Amadis Chemical Company Limited | 58 |
| J & K SCIENTIFIC LTD. | 76 |
| VDM Biochemicals | 64 |
1135242-13-5(VU 0357017 hydrochloride)Related Search:
N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide
VU 0285683
VU0155041
VU0134992(hydrochloride)
VU6005649
VU 591 hydrochloride
VU0810464
VU0483605
N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide
1-(4-Methoxybenzyl)-5-trifluoromethoxyisatin
VU 6008667
(1R,2R)-N-([S]-1-{4-[5-broMo-2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxaMide
5-Amino-3,4-dimethyl-thieno[2,3-c]pyridazine-6-carboxylic acid 4-trifluoromethanesulfonyl-benzylamide
3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine
VU 0360172
1of4
VU 0357017 hydrochloride
4-[[2-[(2-Methylbenzoyl)aMino]ethyl]aMino]-1-piperidinecarboxylic Acid Ethyl Ester Hydrochloride
4-[[2-[(2-Methylbenzoyl)amino]ethyl]amino]-1-piperidinecarboxylic acid ethyl ester monohydrochloride
CID 25010775
Ethyl 4-(2-(2-methylbenzamido)ethylamino)piperidine-1-carboxylate hydrochloride
ML071 hydrochloride
SID 56353039
VU0357017 monohydrochloride
VU0357017
VU0-357017;VU 0357017;CID-25010775; VU-0357017 HYDROCHLORIDE; VU 0357017 HYDROCHLORIDE
CS-2319
VU0357017 HCI
Muscarinic acetylcholine receptor,CID 25010775,VU 0357017,muscarinic,Inhibitor,inhibit,VU-0357017 hydrochloride,VU0357017 hydrochloride,VU0357017,mAChR,VU-0357017,CID25010775,acetylcholine,Alzheimer’s,schizophrenia
1135242-13-5
C18H27N3O3HCl
Aromatics
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals
Positive allosteric modulator of muscarinic M1 receptors.
Amines