2-CHLOROLEPIDINE
- CAS No.
- 634-47-9
- Chemical Name:
- 2-CHLOROLEPIDINE
- Synonyms
- AKOS BB-6898;Chlorolepidine;3-chlorolepidine;2-CHLOROLEPIDINE;AKOS BBS-00000215;Lepidine, 2-chloro-;2-Chlorolepidine >OTAVA-BB BB0116110026;2-chloro-4-methyl-quinolin;2-CHLORO-4-METHYLQUINOLINE
- CBNumber:
- CB9663910
- Molecular Formula:
- C10H8ClN
- Molecular Weight:
- 177.63
- MDL Number:
- MFCD00006742
- MOL File:
- 634-47-9.mol
- MSDS File:
- SDS
| Melting point | 55-58 °C(lit.) |
|---|---|
| Boiling point | 296 °C(lit.) |
| Density | 1.1810 (rough estimate) |
| refractive index | 1.6224 (estimate) |
| Flash point | 296°C |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 0.98±0.50(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| BRN | 118333 |
| CAS DataBase Reference | 634-47-9(CAS DataBase Reference) |
| FDA UNII | 2U5ATH9EJR |
| NIST Chemistry Reference | Quinoline, 2-chloro-4-methyl-(634-47-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39-36-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29334900 | |||||||||
| NFPA 704 |
|
2-CHLOROLEPIDINE price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C0191 | 2-Chlorolepidine >98.0%(GC) | 634-47-9 | 5g | $44 | 2024-03-01 | Buy |
| TCI Chemical | C0191 | 2-Chlorolepidine >98.0%(GC) | 634-47-9 | 25g | $146 | 2024-03-01 | Buy |
| Alfa Aesar | H26504 | 2-Chloro-4-methylquinoline, 99% | 634-47-9 | 5g | $47.65 | 2024-03-01 | Buy |
| Alfa Aesar | H26504 | 2-Chloro-4-methylquinoline, 99% | 634-47-9 | 25g | $151.65 | 2024-03-01 | Buy |
| TRC | C587370 | 2-Chloro-4-methyl-quinoline | 634-47-9 | 5G | $55 | 2021-12-16 | Buy |
2-CHLOROLEPIDINE Chemical Properties,Uses,Production
Description
4-Methyl-2-chloro-quinoline is an organic intermediate. It has been reported that it can be used to prepare graphite electrodes based on CrO-FeO-PbO and quinoline modified and a modified vermiculite adsorbent for the adsorption and removal of benzene in chemical wastewater.
Preparation
The mixture of 2-hydroxy-4-methylquinoline and phosphorus oxychloride was heated to 80-85°C. After the solid was completely dissolved, the mixture was poured into ice water, the mixture was extracted with ether, and the ether extract was distilled out of ether. Afterwards, carry out vacuum distillation, collect 132-135 ℃ (0.4kPa) fraction, namely 2-chloro-4-methylquinoline. For further purification, petroleum ether (boiling point 40-50°C) can be used for recrystallization, and the yield is 86%-89%.
Chemical Properties
white to light yellow crystal powder
Uses
2-Chloro-4-methyl-quinoline is a useful synthetic intermediate. It is an intermediate used to synthesize 4-Methyl-2-(1-piperidinyl)-quinoline (M320715) which is a potent inhibitor of TRPC4 channels, responsible for various stimulation, muscle response due to interaction with the environment. 2-Chloro-4-methyl-quinoline is also considered as a cyanine dye.
Synthesis Reference(s)
Journal of the American Chemical Society, 63, p. 2367, 1941 DOI: 10.1021/ja01854a016
Organic Syntheses, Coll. Vol. 3, p. 194, 1955
2-CHLOROLEPIDINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81148696 +8615536356810 | 1047@dideu.com | China | 3306 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| WinWin Chemical CO., Limited | +86-0577-64498589 +8615325081899 | sales@win-winchemical.com | China | 13854 | 58 |
View Lastest Price from 2-CHLOROLEPIDINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-03-07 | 2-CHLOROLEPIDINE
634-47-9
|
US $1.10 / g | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2021-10-15 | 2-CHLOROLEPIDINE
634-47-9
|
US $10.00 / KG | 1KG | 99% | 20 Tons | Hebei Zhanyao Biotechnology Co. Ltd | |
 |
2020-04-30 | 2-CHLOROLEPIDINE
634-47-9
|
US $0.10 / KG | 1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- 2-CHLOROLEPIDINE
634-47-9
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 2-CHLOROLEPIDINE
634-47-9
- US $10.00 / KG
- 99%
- Hebei Zhanyao Biotechnology Co. Ltd
-
- 2-CHLOROLEPIDINE
634-47-9
- US $0.10 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
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