マラリキシバット塩化物 化学特性,用途語,生産方法
効能
肝保護薬, ナトリウム胆汁酸共輸送体阻害薬
説明
Marilixibat chloride is an oral small-molecule ileal bile acid transporter (IBAT)
inhibitor developed by Mirum Pharmaceuticals and approved by
the USFDA for cholestatic pruritus in patients with Alagille
syndrome (ALGS). IBAT facilitates reabsorption of bile acids
from the ileum and is a key facilitator of bile acid enterohepatic
recirculation. Similar to surgical interruption of enterohepatic
recirculation, it was shown that inhibition of IBAT with 22
reduced pruritis in patients with ALGS.
マラリキシバット塩化物 上流と下流の製品情報
原材料
準備製品