17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA

 化学構造式
221246-34-0
CAS番号.
221246-34-0
化学名:
别名:
英語名:
17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA
英語别名:
CMLNDCUXASGBMQ-NQUQXYBYSA-N;17-trifluoromethylphenyl trinor Prostaglandin F2α;17-trifluoromethylphenyl trinor Prostaglandin F2α;17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA;9ALPHA,11ALPHA,15S-TRIHYDROXY-17-TRIFLUOROMETHYLPHENYL-18,19,20-TRINOR-PROSTA-5Z,13E-DIEN-1-OIC ACID;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]-1-penten-1-yl]cyclopentyl]-, (5Z)-
CBNumber:
CB3320675
化学式:
C24H31F3O5
分子量:
456.5
MOL File:
221246-34-0.mol

17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA 物理性質

沸点 :
593.0±50.0 °C(Predicted)
比重(密度) :
1.296±0.06 g/cm3(Predicted)
貯蔵温度 :
Store at -20°C
溶解性:
DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml
酸解離定数(Pka):
4.76±0.10(Predicted)

安全性情報

17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA 化学特性,用途語,生産方法

説明

A number of 17-phenyl trinor prostaglandin F (17-phenyl trinor PGF) derivatives have been approved for the treatment of glaucoma. Of these, the unsubstituted or meta-substituted aromatic derivatives are the most potent FP receptor agonists. 17-trifluoromethylphenyl trinor PGF bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl trinor PGF would act very much like the free acid of travoprost. 17-phenyl trinor PGF is a potent luteolytic and abortifacient, with a potency equal to or greater than fluprostenol and cloprostenol.

17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA 上流と下流の製品情報

原材料

準備製品


17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA 生産企業

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221246-34-0()キーワード:


  • 221246-34-0
  • 9ALPHA,11ALPHA,15S-TRIHYDROXY-17-TRIFLUOROMETHYLPHENYL-18,19,20-TRINOR-PROSTA-5Z,13E-DIEN-1-OIC ACID
  • 17-trifluoromethylphenyl trinor Prostaglandin F2α
  • 17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA
  • CMLNDCUXASGBMQ-NQUQXYBYSA-N
  • 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]-1-penten-1-yl]cyclopentyl]-, (5Z)-
  • 17-trifluoromethylphenyl trinor Prostaglandin F2α
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