AMG-51

AMG-51 価格

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AMG-51 化学特性,用途語,生産方法

酵素阻害剤

This protein kinase inhibitor (FW = 629.65 g/mol; CAS 890019-63-3; Solubility: 15 mM in DMSO), also known as 5-(3-fluoro-4-(6-methoxy-7- (3-morpholinopropoxy)quinolin-4-yloxy)phenyl)-2-(4-fluorophenylamino)-3-methylpyrimidin-4(3H)-one, targets c-Met, or hepatocyte growth factor receptor (HGFR), a protein tyrosine kinase that plays a key role in several cellular processes and is overexpressed or mutated in different human cancers. AMG-51 shows the enzyme selectivity of c-Met with a (Ki = 4.9 nM), with off-targets, such as IGFR (Ki = 22nM), Ron or Recepteur d'Origine Nantais kinase (Ki = 28nM), and KDR (Ki = 139 nM).

AMG-51 上流と下流の製品情報

原材料

準備製品

AMG-51 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
SYN|thesis med chem P/L	+86-021-50720296	service@synkinase.com	China	266	58
Pharmacodia (Beijing) Co.,Ltd	+86-400-851-9921	sales@pharmacodia.com	China	2317	55
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Zhongshan Geometric Biological Technology Co., Ltd.	+86-13168912896		China	253	58
Lynnchem	86-(0)29-85992781 17792393971	info@lynnchem.com	China	4587	58
Novachemistry	44-20819178-90 02081917890	info@novachemistry.com	United Kingdom	4381	58
Shanghai Biopharmaleader Co., Ltd.	+86 18721201413	sales@biopharmaleader.com	China	1720	58
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8618	58

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• 890019-63-3
• AMG-51
• 5-[3-Fluoro-4-[[6-Methoxy-7-(3-Morpholinopropoxy)quinolin-4-yl]oxy]phenyl]-2-(4-fluorophenylaMino)-3-MethylpyriMidin-4(3H)-one
• 2-(4-fluoroanilino)-5-[3-fluoro-4-[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxyphenyl]-3-methylpyrimidin-4-one
• AMG-51 (KRC547)
• 4(3H)-Pyrimidinone, 5-[3-fluoro-4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinolinyl]oxy]phenyl]-2-[(4-fluorophenyl)amino]-3-methyl-