4-アミノ-5-(4-フェノキシフェニル)-7-シクロペンチル-7H-ピロロ[2,3-d]ピリミジン

4-アミノ-5-(4-フェノキシフェニル)-7-シクロペンチル-7H-ピロロ[2,3-d]ピリミジン 価格 もっと(2)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
Sigma-Aldrich Japan	C8863	≥98% (HPLC) 7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3?d]pyrimidin-4-ylamine ≥98% (HPLC)	213743-31-8	5mg	￥24800	2024-03-01	購入
Sigma-Aldrich Japan	C8863	≥98% (HPLC) 7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3?d]pyrimidin-4-ylamine ≥98% (HPLC)	213743-31-8	25mg	￥115000	2024-03-01	購入

4-アミノ-5-(4-フェノキシフェニル)-7-シクロペンチル-7H-ピロロ[2,3-d]ピリミジン 化学特性,用途語,生産方法

使用

Lck Inhibitor is a cell-permeable ATP-competitive inhibitor of Lck.

一般的な説明

A cell-permeable pyrrolopyrimidine compound that acts as a potent, reversible, selective, and ATP-competitive inhibitor of Lck (IC₅₀ at 5 μM ATP = <1 nM, 2 nM, 70 nM, 1.57 μM and 1.98 μM for lck_64-509 Y³⁹⁴, Lckcd pY³⁹⁴, Src, Kdr and Tie-2, respectively; IC₅₀ at 1 mM ATP = 16 μM, 66 nM, 126 nM, 420 nM and 5.18 μM for Lck_64-509 Y³⁹⁴, Blk, Fyn, Lyn and Csk, respectively). Only minimally affects the activities of other kinases (IC₅₀ = 3.2 μM, >33 μM, >50 μM and >50 μM for EGFR, PKC, CDC2/B and ZAP-70, respectively). Also shown to potently block T-cell receptor-stimulated IL-2 production in vitro (IC₅₀<1-40 nM in Jurkat T cells) and in vivo (ED₅₀ = 4 mg/kg in mice, ip.)

Biochem/physiol Actions

Primary TargetLck?????? Y3

4-アミノ-5-(4-フェノキシフェニル)-7-シクロペンチル-7H-ピロロ[2,3-d]ピリミジン 上流と下流の製品情報

原材料

準備製品

4-アミノ-5-(4-フェノキシフェニル)-7-シクロペンチル-7H-ピロロ[2,3-d]ピリミジン 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32715	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Nanjing Doge Biomedical Technology Co., Ltd	+86-25-58227606 +86-15305155328	sales@dogechemical.com	China	4128	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
Shanghai JiYi Biotechnology Co. Ltd.	13621943973	sales@shjiyipharmatech.com	China	1166	55
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80

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• 213743-31-8
• 7-CYCLOPENTYL-5-(4-PHENOXY)PHENYL-7H-PYR
• 7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• RK-24466 ;RK 24466 ;RK24466
• Lck Inhibitor - CAS 213743-31-8 - Calbiochem
• d]pyrimidin-4-ylamine
• RK-24466
• KIN 001-51
• 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-cyclopentyl-5-(4-phenoxyphenyl)-
• KIN001-051
• RK-24466,Src,Inhibitor,inhibit,RK 24466,RK24466
• 4-Amino-7-cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidine
• 7-シクロペンチル-5-(4-フェノキシフェニル)-7H-ピロロ[2,3-d]ピリミジン-4-アミン
• 4-アミノ-5-(4-フェノキシフェニル)-7-シクロペンチル-7H-ピロロ[2,3-d]ピリミジン
• 5-(4-フェノキシフェニル)-7-シクロペンチル-7H-ピロロ[2,3-d]ピリミジン-4-アミン