ONO-4817 化学特性,用途語,生産方法
使用
MMP Inhibitor V is a broad-spectrum inhibitor of matrix metalloproteinase (MMPs).
生物活性
Broad spectrum MMP inhibitor; K i values are 0.45, 0.73, 1.1, 1.1, 2.1, 42 and 2500 nM for MMP-12, MMP-2, MMP-8, MMP-13, MMP-9, MMP-3 and MMP-7 respectively and IC 50 = 1600 nM for MMP-1). Displays no activity at other proteases up to a concentration of 100 μ M. Exhibits antiangiogenic and anti-invasive properties on lung metastasis of murine renal cell carcinoma.
ONO-4817 上流と下流の製品情報
原材料
準備製品