2,4-ジメチルアニリン 化学特性,用途語,生産方法
外観
無色〜暗赤褐色, 澄明の液体
溶解性
エタノール及びアセトンに極めて溶けやすく、水に溶ける。
用途
有機合成試薬。
使用上の注意
不活性ガス封入
化学的特性
colourless to yellow or dark brown liquid
使用
2,4-Xylidine, as part of the commercial mixture, has the same
uses as xylidine.
定義
ChEBI: A primary arylamine that is aniline in which the hydrogens at the 2- and 4-positions are replaced by methyl groups. A clear to yellow liquid, it is used in production of certain dyes, pesticides and other chemicals.
一般的な説明
Dark brown liquid.
空気と水の反応
2,4-Dimethyl aniline may be sensitive to prolonged exposure to air. Slightly soluble in water.
反応プロフィール
2,4-Dimethyl aniline ignites on contact with fuming nitric acid . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
火災危険
2,4-Dimethyl aniline is combustible.
安全性プロファイル
Suspected carcinogen.
Poison by ingestion. Mutation data reported. When heated to decomposition it emits
toxic fumes of NOx. See also other xylidine
entries.
代謝経路
The major urinary metabolite of 2,4-dimethylaniline
(2,4-DMA) in rats is N-acetyl-4-amino-3-methylbenzoic
acid, while in dogs, it is 6-hydroxy-2,4-dimethylaniline.
Dogs also produce a smaller amount of unacetylated
4-amino-3-methylbenzoic acid and its glycine
conjugate. 2,6-Dimethylaniline (2,6-DMA) is
metabolized principally to 4-hydroxy-2,6-
dimethylaniline in both species, but dogs also produce
a significant quantity of 2-amino-3-methylbenzoic acid along with a trace amount of the glycine conjugate of
the latter metabolite and 2,6-dimethylnitrosobenzene.
Trace levels of an unknown postulated to be 3,5-
dimethyl-4-iminoquinone are found in dog urine.
純化方法
Convert uns-xylidine to a derivative (see below) which, after recrystallisation, is decomposed with alkali to give the free base. Dry it over KOH and fractionally distil. The acetyl derivative has m 130o, the benzoyl derivative has m 192o, and the picrate has m 209o. [Beilstein 12 H 1111, 12 IV 2545.]
2,4-ジメチルアニリン 上流と下流の製品情報
原材料
準備製品
N1-(2,4-ジメチルフェニル)-N2-メチルホルムアミジン·塩酸塩
6-アミノ-2-(2,4-ジメチルフェニル)-2H-ベンゾ[de]イソキノリン-1,3-ジオン
2,6-ジメチルアニリン
4-ヒドロキシ-3-(フェニルアゾ)-2(1H)-キノリノン
アミトラズ
4-ブロモ-m-キシレン
1,4-ジシアノナフタレン
3-ニトロ-2,4-キシリジン
4-クロロ-m-キシレン
5,7-ジメチル-1H-インドール-2,3-ジオン
2,4-ジメチル-5-ニトロベンゼンアミン
2,4-ジメチルフェニルヒドラジン塩酸塩
Naphtho[2,1-d]thiazole-8-sulfonic acid, 2-(3-aminophenyl)-7-[(2,4-dimethylphenyl)azo]-6-hydroxy-, monosodium salt
5-(アセチルアミノ)-3-[(ジメチルフェニル)アゾ]-4-ヒドロキシ-2,7-ナフタレンジスルホン酸ジナトリウム
2,4-ビス[(2,4-ジメチルフェニル)アゾ]-1,3-ベンゼンジオール
Direct Red 264
4-ヒドロキシ-3-[(2,4-ジメチルフェニル)アゾ]-1-ナフタレンスルホン酸ナトリウム