STK393606

STK393606 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入

STK393606 化学特性,用途語,生産方法

説明

15-hydroxy prostaglandin dehydrogenase (15-hydroxy PGDH) is a key enzyme involved in the inactivation of PGs and related eiscosanoids. It functions by catalyzing the oxidation of primary PGs to their 15-keto metabolites. Two types of 15-hydroxy PGDH have been identified: type-I is NAD⁺-dependent primarily using eicosanoids as substrates, while type-II uses either NAD⁺ or NADP⁺ as cofactors and bears broader substrate specificity. STK393606 is a competitive inhibitor of NAD⁺-dependent type-I 15-hydroxy PGDH with an IC₅₀ value of 26.4 nM and a K_i value of 5 nM. It demonstrates selectivity for 15-hydroxy PGDH when profiled across a panel of related dehydrogenase or reductase enzymes.

STK393606 上流と下流の製品情報

原材料

準備製品

STK393606 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
BOC Sciences	16314854226	info@bocsci.com	United States	9926	65
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8740	58
ApexBio Technology	--	sales@apexbt.com	United States	6254	58

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• 355827-05-3
• STK393606
• 2-(6-Bromo-3H-imidazo[4,5-b]pyridin-2-ylsulfanylmethyl)-benzonitrile
• 2-[(6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)sulfanylmethyl]benzonitrile
• Benzonitrile, 2-[[(6-bromo-3H-imidazo[4,5-b]pyridin-2-yl)thio]methyl]-