チオりん酸O,O-ジメチルO-[2-(ジエチルアミノ)-6-メチル-4-ピリミジニル] 化学特性,用途語,生産方法
外観
無色～わずかにうすい黄色, 澄明の液体
溶解性
アルコール、ケトンなどと混和する。水:9.9(pH5.2)、8.6(pH7.3)、9.3(pH9.3)(全てmg/l 30℃)水9.9(pH 5.2), 8.6(pH 7.3), 9.3(pH 9.3)(全てmg/l30℃)。アルコール, ケトンなどと混和する。アセトンに溶け、水にほとんど溶けない。
農薬用途
殺虫剤、ダニ駆除剤
化学的特性
Light yellow, straw colored, or amber oily liquid. Odorless when pure.
使用
Pirimiphos-methyl is a phosphorothioate used as an insecticide. Pirimiphos-methyl is commonly used for mosquito control as well as control of greenhouse crop pests and stored-product insects.
定義
ChEBI: An organic thiophosphate that is O,O-dimethyl O-pyrimidin-4-yl phosphorothioate substituted by a methyl group at position 6 and a diethylamino group at position 2.
一般的な説明
Yellow liquid. Corrosive to tin and mild steel. Used as an insecticide.
空気と水の反応
Hydrolyzed by strong acid or base.
反応プロフィール
Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
农业用途
Insecticide, Acaricide: Pirimiphos-methyl is a post-harvest insecticide used to control a variety of insects in stored grain products and seed such as corn, rice, wheat and sorghum. It is also incorporated into cattle ear tags, and used for the fogging treatment of iris bulbs and pre-harvest clean up of fruits and vegetables.
製品名
ACTELLIC®; ACTELLIFOG®; BLEX®; ENT 27699Gc®; DOMINATOR® EAR TAG; DOUBLE BARREL® EAR TAG; PLANT PROTECTION PP511®; PP511®; SILOSAN®; SYBOL®; TOMAHAWK®[C]
安全性プロファイル
Moderately toxic by
ingestion. Mutation data reported. When
heated to decomposition it emits very toxic
fumes of NOx, POx, and SOx.
職業ばく露
Pirimiphos-methyl is a post -harves organophosphate insecticide/acaricide used to control a variety of insects in stored grain products and seed such as corn, rice, wheat and sorghum. It is also incorporated into cattle ear tags, and used for the fogging treatment of iris bulbs and preharvest cleanup of fruits and vegetables.
発がん性
When rats were given diets with
0, 10, 50, or 300 ppm pirimiphos methyl (equivalent to 0, 0.4,
2.1, or 12.6 mg/kg/day) for 2 years, 4 of the 42 high-dose
male rats had pancreatic islet cell adenomas and 1 had a
carcinoma compared to none in control male rats .
In a carcinogenicity study, mice were given diets with 0,
50, 200, or 400/300 ppm pirimiphos methyl (equivalent to 0,
8.3, 33, or 52 mg/kg/day (males); 0, 9.7, 39, or 61 mg/kg/day (females)) for 78 weeks . The initial 400 ppm dose
resulted in excessive toxicity and moribundity and was
reduced to 300 ppm after 8 days. There was no evidence
of carcinogenicity. In another mouse carcinogenicity study,
pirimiphos methyl was administered in the diet at levels of 0,
5, 250, or 500 ppm (equivalent to 0, 0.5, 25.9, or 45.0 mg/kg/
day (males) and 0, 0.6, 27.6, or 50.6 mg/kg/day (females),
respectively) for 80 weeks. The test diet for the highest dose
groups initially contained 300 ppm of the test compound (the
duration of treatment was not specified). The dose was then
increased weekly by 50 ppm to 500 ppm. No evidence of
carcinogenicity was observed.
代謝経路
The metabolism of pirimiphos-methyl is similar in soils, plants and animals
and can be represented by initial hydrolysis to yield 2-diethylamino-
6-methyl-p yrimidin-4-0l which may be either conjugated or successively
N-de-ethylated. In plants, pirimiphos-methyl itself is N-de-ethylated. It is
probable that the oxon form of the compound is formed in many systems
but it is more labile than the parent compound and is often not detected.
0-Dealkylation, as with most organophosphates, is most probably a
major detoxification route in mammals but the evidence for it in the
case of pirimiphos-methyl is poor.
輸送方法
UN2783 Organophosphorus pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN3018 Organophosphorus pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
不和合性
May react violently with antimony(V) pentafluoride. Incompatible with strong acids and alkalies, lead diacetate, magnesium, silver nitrate. In the presence of strong reducing agents such as hydrides, organophosphates form highly toxic and flammable phosphine gas. Contact with oxidizers can cause the release of toxic oxides of phosphorus.
廃棄物の処理
Destruction by alkali hydrolysis or incineration. Containers must be disposed of properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.
チオりん酸O,O-ジメチルO-[2-(ジエチルアミノ)-6-メチル-4-ピリミジニル] 上流と下流の製品情報
原材料
準備製品