Polyhexamethyleneguanidine phosphate

 化学構造式
89697-78-9
CAS番号.
89697-78-9
化学名:
别名:
英語名:
Polyhexamethyleneguanidine phosphate
英語别名:
PHMG-P;PHMG phosphate;POLYHEXAMETHYLENE GUANIDINE PHOSPHATE;PHMG phosphate/ Polyhexamethyleneguanidine phosphate;Poly(iminoimidocarbonyliminohexamethylene) phosphate
CBNumber:
CB81014693
化学式:
C21H45N9X2.3H3O4P
分子量:
717.631
MOL File:
89697-78-9.mol

Polyhexamethyleneguanidine phosphate 物理性質

安全性情報

Polyhexamethyleneguanidine phosphate 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

Polyhexamethyleneguanidine phosphate 化学特性,用途語,生産方法

使用

Polyhexamethyleneguanidine phosphate (PHMG-P) has been widely used as a disinfectant because of its strong bactericidal activity and low toxicity.

Toxicity evaluation

Administration of PHMG-P induced proinflammatory cytokines elevation and infiltration of immune cells into the lungs. Histopathological analysis revealed a dose-dependent exacerbation of both inflammation and pulmonary fibrosis on day 14. PHMG-P also decreased the total cell number and the CD4+/CD8+ cell ratio in the thymus, with the histopathological examination indicating severe reduction of cortex and medulla. The mRNA levels of biomarkers associated with T cell development also decreased markedly. These findings suggest that exposure of lung tissue to PHMG-P leads to pulmonary inflammation and fibrosis as well as thymic atrophy.

Polyhexamethyleneguanidine phosphate 上流と下流の製品情報

原材料

準備製品


Polyhexamethyleneguanidine phosphate 生産企業

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