フューリンインヒビターII
フューリンインヒビターII 物理性質
- 比重(密度) :
- 1.59±0.1 g/cm3(Predicted)
- 貯蔵温度 :
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- 溶解性:
- H2O : 50 mg/mL (52.40 mM; Need ultrasonic)DMSO : 5 mg/mL (5.24 mM; Need ultrasonic)
- 酸解離定数(Pka):
- 13.24±0.46(Predicted)
- 外見 :
- 凍結乾燥
- 水溶解度 :
- Soluble to 2 mg/ml in water
フューリンインヒビターII 価格
もっと(1)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
Sigma-Aldrich Japan
|
SCP0148 |
フューリンインヒビターII
Furin Inhibitor II |
673202-67-0 |
5mg |
￥66600 |
2024-03-01 |
購入 |
フューリンインヒビターII 化学特性,用途語,生産方法
使用
Furin Inhibitor II has been used as a furin inhibitor:
- to study its effects on transforming growth factor β1 (TGF-β1) induced glial cell line-derived neurotrophic factor (GDNF) production in non-tumorigenic immortalized human granulosa cell line (SVOG).
- to study its effect on cleavage of (Pro) renin receptor (PRR) induced by bovine serum albumin (BSA) in human kidney 2 (HK-2) cells.
- in furin cleavage assay.
一般的な説明
Furin is a calcium-dependent serine endoproteinase and belongs to the subtilisin-like proprotein/prohormone convertase (PC) family. It is distributed ubiquitously and has a rhythmic movement between the trans-Golgi network, cell surface and the endosomes.
Biochem/physiol Actions
Furin plays a role in processing several pro-proteins such as, bone morphogenetic protein?4 (BMP-4), insulin receptor and Notch1 receptor. It also processes human immune deficiency virus 1 (HIV-1) glycoprotein gp160, several metalloproteases?and pro-β-nerve growth (pro-β-NGF) factor. Furin is also involved in cleaving transforming growth factor β1 (TGF-β1).
フューリンインヒビターII 上流と下流の製品情報
原材料
準備製品
フューリンインヒビターII 生産企業
Global( 71)Suppliers
673202-67-0(フューリンインヒビターII)キーワード:
- 673202-67-0
- HEXA-D-ARGININE
- H-(D)RRRRRR-NH2
- FURIN INHIBITOR II
- H-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-NH2
- Hexa-D-arginine aMide
- D-ArgininamideD-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-alanine
- Furin Inhibitor II, >98%
- Hexa-D-arginine,RRRRRR
- D-Argininamide, D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl- (9CI)
- D-Argininamide,D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-
- inhibit,furin,Furin Inhibitor II,TNF-α,PACE4,noncytotoxic,PC1,anthrax,PEA,HexaDarginine,Hexa D arginine,exotoxins,Inhibitor
- Furin Inhibitor II(Hexa-D-arginine)
- フューリンインヒビターII