COLISTIN

COLISTIN 구조식 이미지
카스 번호:
1066-17-7
동의어(한글):
콜리스틴
상품명:
COLISTIN
동의어(영문):
COLISTIN;kangdisu;totazina;colomycin;colimycin;Aids033059;coly-mycin;colymysins;kolimitsin;Aids-033059
CBNumber:
CB0169873
분자식:
C52H98N16O13
포뮬러 무게:
1155.43
MOL 파일:
1066-17-7.mol

COLISTIN 속성

끓는 점
807.67°C (rough estimate)
밀도
1.1050 (rough estimate)
굴절률
1.6700 (estimate)
저장 조건
Store at -20°C
용해도
PBS (pH 7.2): 10 mg/ml
CAS 데이터베이스
1066-17-7

안전

유엔번호(UN No.) 3249
위험 등급 6.1(b)
포장분류 III
유해 물질 데이터 1066-17-7(Hazardous Substances Data)
독성 cat,LDLo,subcutaneous,250mg/kg (250mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITINGBEHAVIORAL: ATAXIABEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY),Antibiotiki. Vol. 5(4), Pg. 10, 1960.

COLISTIN C화학적 특성, 용도, 생산

용도

Polymyxin E (colistin) is a complex of closely related cyclic peptides E1 and E2, with additional minor analogues. Polymyxin E is produced by Bacillus polymyxa var. colistinus, and is a highly basic, atypical cyclic peptide which incorporates the unusual amino acid, diaminobutyric acid. Head-to-tail coupling of lysine completes the macrocycle. Balancing the polar cyclic peptide is a hydrophobic tail with short chain fatty acids. Polymyxin E is a broad spectrum antibiotic active against Gram negative bacteria. The mechanism of action involves disruption of the bacterial outer membrane by a detergent-like effect.

상표명

Coly-Mycin (Monarch).

COLISTIN 준비 용품 및 원자재

원자재

준비 용품


COLISTIN 공급 업체

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