ETHOTOIN
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ETHOTOIN 속성
- 녹는점
- 94°C
- 끓는 점
- 342.72°C (rough estimate)
- 밀도
- 1.1754 (rough estimate)
- 굴절률
- 1.5200 (estimate)
- 저장 조건
- Refrigerator
- 용해도
- 디클로로메탄(약간 용해됨), DMSO(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 8.01±0.70(Predicted)
- 색상
- 흰색에서 황백색까지
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험 카페고리 넘버 | 22 | ||
|---|---|---|---|
| HS 번호 | 2933210000 | ||
| 유해 물질 데이터 | 86-35-1(Hazardous Substances Data) |
ETHOTOIN C화학적 특성, 용도, 생산
용도
Ethotoin is a hydantoin based anticonvulsant drug used in the treatment of epilepsy.정의
ChEBI: An imidazolidine-2,4-dione that is hydantoin substituted by ethyl and phenyl at positions 3 and 5, respectively. An antiepileptic, it is less toxic than phenytoin but also less effective.신진 대사
Ethotoin differs from phenytoin in that one phenyl substituent at position 5 has been replaced by hydrogen, and the N-H at position 3 is replaced by an ethyl group. It may be indicated for treatment of tonic-clonic and complex partial (psychomotor) seizures. Because it is considered to be less toxic but also less effective and more sedating than phenytoin, ethotoin usually is reserved for use as an add-on drug. Ethotoin does not share phenytoin's profile of antiarrhythmic action. The metabolism of ethotoin, like phenytoin, is saturable and nonlinear. Its administration is contraindicated in patients with hepatic abnormalities and hematologic disorders.Purification Methods
It is an anticonvulsant and is used in epilepsy. [Dudley et al. J Heterocycl Chem 10 173 1973, Pinner Chem Ber 21 2320 1888, Beilstein 25 III/IV 963, 27 II 860.]ETHOTOIN 준비 용품 및 원자재
원자재
준비 용품
ETHOTOIN 공급 업체
글로벌( 31)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32686 | 60 |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 |
1026@dideu.com | China | 9020 | 58 |
| Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 |
shchemsky@sina.com | China | 32344 | 50 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 |
sj_scrc@sinopharm.com | China | 9823 | 79 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 |
info@SuperLan-chem.com | China | 9737 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 |
sales@rrkchem.com | China | 55827 | 58 |
| BOC Sciences | -- |
info@bocsci.com | USA | 0 | 65 |
| Hefei fuya biotechnology co. LTD | 18096409024 |
sales02@foreversyn.com | China | 1947 | 58 |
ETHOTOIN 관련 검색:
히단토인
ETHOTOIN
5-Phenylhydantoin
Ropitoin
(+/-)-N-3-Benzylnirvanol
[4-(4-METHOXY-PHENYL)-4-METHYL-2,5-DIOXO-IMIDAZOLIDIN-1-YL]-ACETIC ACID
5,5-DIPHENYLHYDANTOIN-3-BUTYRIC ACID
(2,5-DIOXO-3',4'-DIHYDRO-1H,2'H-SPIRO[IMIDAZOLIDINE-4,1'-NAPHTHALEN]-1-YL)ACETIC ACID
1-(4-(2-Hydroxyethyl)-1-piperazine-2-propanolo)-3-ethyl-5,5-diphenylhy dantoin 2HCl hydrate
[4-(4-FLUOROPHENYL)-4-METHYL-2,5-DIOXOIMIDAZOLIDIN-1-YL]ACETIC ACID
(4-[4-(2-AMINO-2-OXOETHOXY)PHENYL]-4-METHYL-2,5-DIOXOIMIDAZOLIDIN-1-YL)ACETIC ACID
2,4-Imidazolidinedione, 5,5-diphenyl-3-ethyl-1-(2-hydroxy-3-(1-piperid inyl)propyl)-, monohydrochloride
[4-METHYL-4-(2-NAPHTHYL)-2,5-DIOXOIMIDAZOLIDIN-1-YL]ACETIC ACID
[4-METHYL-4-(4-METHYLPHENYL)-2,5-DIOXOIMIDAZOLIDIN-1-YL]ACETIC ACID
(4-ETHYL-2,5-DIOXO-4-PHENYLIMIDAZOLIDIN-1-YL)ACETIC ACID
(4-METHYL-2,5-DIOXO-4-PHENYL-IMIDAZOLIDIN-1-YL)-ACETIC ACID
(2',5'-DIOXO-2,3-DIHYDRO-1'H-SPIRO[CHROMENE-4,4'-IMIDAZOLIDIN]-1'-YL)ACETIC ACID
(2,5-DIOXO-2',3'-DIHYDRO-1H-SPIRO[IMIDAZOLIDINE-4,1'-INDEN]-1-YL)ACETIC ACID