프로트리프틸린

프로트리프틸린
프로트리프틸린 구조식 이미지
카스 번호:
438-60-8
한글명:
프로트리프틸린
동의어(한글):
프로트리프틸린;프로트리프틸라인
상품명:
PROTRIPTYLINE
동의어(영문):
Triptil;Vivactil;Amimetilina;Protriptylin;PROTRIPTYLINE;Protryptyline;Protriptyline-d6;Protriptyline 13CD3;DIBENZO(A,D)CYCLOHEPTENE-5-PROPYLAMINE,N-METHYL-;3-(dibenzo(a,d)cyclohepten-5-yl)propylmethylamine
CBNumber:
CB0774981
분자식:
C19H21N
포뮬러 무게:
263.38
MOL 파일:
438-60-8.mol

프로트리프틸린 속성

끓는 점
396.62°C (rough estimate)
밀도
0.9076 (rough estimate)
굴절률
1.7500 (estimate)
산도 계수 (pKa)
8.2(at 25℃)
EPA
Protriptyline (438-60-8)

안전

유해 물질 데이터 438-60-8(Hazardous Substances Data)

프로트리프틸린 C화학적 특성, 용도, 생산

용도

Protriptyline is a powerful antidepressant, the mechanism of action of which is not known. It is not a MAO inhibitor and does not stimulate the CNS. It begins to act much faster and acts much longer than imipramine or amitriptyline. Protriptyline does not possess sedative tranquilizing properties. It is used in clinical conditions for treating severe depression.

Mechanism of action

Protriptyline exhibits high selectivity for the NE transporter, but with less potency than desipramine. Its mechanism of action is similar to that of desipramine. Minimal effect on 5-HT reuptake has been observed.

신진 대사

Protriptyline is a dibenzocycloheptriene TCA that differs from the other tricyclics by having an unsaturated ethylene bridge joining the two aromatic rings and a secondary aminopropyl side chain. Protriptyline is completely absorbed from the GI tract and slowly eliminated. Metabolism data are limited for protriptyline, but it is most likely to be metabolized via the same pathways as the other TCAs are. Very little drug is excreted in the feces via the bile.

프로트리프틸린 준비 용품 및 원자재

원자재

준비 용품


프로트리프틸린 공급 업체

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