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도카르파민

도카르파민 구조식 이미지

카스 번호:: 74639-40-0

한글명:: 도카르파민

동의어(한글):: 도카르파민;도파민

상품명:: Docarpamine

동의어(영문):: TA 870;TA-8704;Tanadopa;Docarpamine;3,4-Bis[(ethoxycarbonyl)oxy]-N-(N-acetyl-L-methionyl)benzeneethanamine;4-{2-[(N-Acetyl-L-methionyl)amino]ethyl}-1,2-phenylenediethylbiscarbonate;(S)-2-(Acetylamino)-N-[3,4-bis(ethoxycarbonyloxy)phenethyl]-4-(methylthio)butanamide;Carbonic acid, 4-[2-[[(2S)-2-(acetylamino)-4-(methylthio)-1-oxobutyl]amino]ethyl]-1,2-phenylene diethyl ester;Carbonic acid, 4-[2-[[2-(acetylamino)-4-(methylthio)-1-oxobutyl]amino]ethyl]-1,2-phenylene diethyl ester, (S)-;Carbonic acid, C,C'-[4-[2-[[2-(acetylamino)-4-(methylthio)-1-oxobutyl]amino]ethyl]-1,2-phenylene] C,C'-diethyl ester

CBNumber:: CB21178560

분자식:: C21H30N2O8S

포뮬러 무게:: 470.54

MOL 파일:: 74639-40-0.mol

속성

안전

용도

공급 업체 10

도카르파민 속성

녹는점: 85-90°; mp 105-108° (Nishiyama, 1992)

알파: D20 -15.6° (c = 2 in methanol)

끓는 점: 731.0±60.0 °C(Predicted)

밀도: 1.222±0.06 g/cm3(Predicted)

산도 계수 (pKa): 14.51±0.46(Predicted)

안전

독성	LD50 in male, female rats (mg/kg): 1000-1400, ~1000 s.c.; in rats, dogs (mg/kg): _>2000 orally (Nishiyama, 1992)

도카르파민 C화학적 특성, 용도, 생산

개요

Docarpamine is a cardiostimulant with diuretic activity launched in Japan for the treatment of circulatory insufficiency. It is an orally effective peripheral dopamine prodrug that is well absorbed from the gastrointestinal tract and converted to dopamine in vivo, which exerts renal vasodilatory and natriuretic effects by activating renal dopamine (DA₁) receptors, and a positive inotropic effect by activating cardiac β1-receptors. It has been reported to be effective in treating patients with acute heart failure, shock and acute renal failure.

용도

Docarpamine maybe a usefule alternative to intravenous dopamine after cardiac surgery.

도카르파민 준비 용품 및 원자재

원자재

준비 용품

도카르파민 공급 업체

글로벌( 10)공급 업체

공급자	전화	이메일	국가	제품 수	이점
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
RR Scientific LLC	+86-13917743231	sales@rrscientific.com	United States	878	58
Weifu (Shanghai) Pharmaceutical Technology Co., LTD	021-57609736 13524092974;	info@shanghaiweifu.cn	China	232	58
SHANGHAI HOHANCE CHEMICAL CO.,LTD	021-31115312 18217084087	mary@hohance.com	China	139	62
Hubei Shishun Biotechnology Co. Ltd	027-59223025 15107168801	1718480011@qq.com	China	9973	58
Hubei Guangao Biotechnology Co., Ltd	027-027-59223056 18162699093	1208480011@qq.com	China	9951	58
Hubei Qifei Pharmaceutical Chemical Co., Ltd	027-59322506 18071128681	1400858811@qq.com	China	9995	58
R.R Scientific, LLC.	15010167677	zhiyuu1218@163.com	China	876	58
Shaanxi Didu New Material Co., Ltd	029-63373950 15353716720	1052@dideu.com	China	10011	58

도카르파민 관련 검색:

N-[2-(4-methoxyphenyl)ethyl]-2-(methylamino)acetamide Docarpamine CARBONIC ACID ETHYL ESTER M-TOLYL ESTER