Isoetharine Hydrochloride

Isoetharine Hydrochloride 구조식 이미지
카스 번호:
50-96-4
상품명:
Isoetharine Hydrochloride
동의어(영문):
Dilabron hydrochloride;Isoetarin hydrochloride;Isoetarine hydrochloride;Isoctarine hydrochloride;Bronkometer hydrochloride;Isoetharine hydrochloride;Etyprenaline hydrochloride;MUFDLGGSOCHQOC-UHFFFAOYSA-N;(R,*)-()-4-[1-hydroxy-2-[(1-methylethyl)amino]butyl]pyrocate...;1-(3,4-Dihydroxyphenyl)-2-isopropylamino-1-butanol hydrochloride
CBNumber:
CB21261224
분자식:
C13H22ClNO3
포뮬러 무게:
275.77
MOL 파일:
50-96-4.mol

Isoetharine Hydrochloride 속성

CAS 데이터베이스
50-96-4

안전

Isoetharine Hydrochloride C화학적 특성, 용도, 생산

용도

Isoetharine Hydrochloride is hydrochloride salt of isoetharine which is β2-adrenergic receptor agonist. It can be used to give quick relief for bronchospasm and asthma. However, It may be potent in producing resistantce to β-adrenoceptor stimulants.

Clinical Use

The α-ethyl group confers β2-selectivity, and the β-hydroxyl group and catechol nucleus makes this a direct-acting drug. It is susceptible to COMT metabolism; however, the α-ethyl group inhibits MAO. Therefore, one would expect some oral activity.

부작용

Isoetharine is dispensed as a solution only for inhalation administration to treat reversible bronchospasm of asthma. It has fallen into relative disuse, because with high doses, there is a significant incidence of cardiovascular (β1-receptor) adverse effects and it has a low β2-receptor potency compared to newer β2-selective agonists. It has a 2- to 4-minute onset of action when inhaled and a duration of action of 3 hours. Isoetharine has adverse effects similar to those of EPI, including palpitations, tachycardia, nausea and vomiting, dizziness, tremor, and headache. Isoetharine may cause decreased levels of theophylline when coadministered. Cardiovascular effects are a concern when isoetharine is taken with other asthma drugs.

Isoetharine Hydrochloride 준비 용품 및 원자재

원자재

준비 용품


Isoetharine Hydrochloride 공급 업체

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