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Capecitabine

Capecitabine 구조식 이미지

카스 번호:: 158798-73-3

상품명:: Capecitabine

동의어(영문):: Caxeta;Capiibine;Hsdb 7656;N(4)-Pentyloxycarbonyl-5'-deoxy-5-fluorocytidine;pentyl N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]carbamate;Pentyl N-[1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-methyl-oxolan-2-yl]-5-fluoro-2-oxo-pyrimidin-4-yl]carbamate;Carbamic acid, (1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl)-, pentyl ester

CBNumber:: CB21503999

분자식:: C15H22FN3O6

포뮬러 무게:: 359.35

MOL 파일:: 158798-73-3.mol

속성

안전

용도

공급 업체 19

Capecitabine 속성

안전

Capecitabine C화학적 특성, 용도, 생산

Originator

Xeloda,Hoffmann - La Roche Inc.,USA

Manufacturing Process

5-Deoxy-5-fluoro-N4-((n-pentyloxy)carbonyl)cytidine may be prepared according to US Patent No. 6,114,520.
From 2',3'-bis-O-(tert-butyldimethylsilyl)-5'-deoxy-5-fluorocytidine and n-pentylchloroformate in dichloromethane and pyridine may be obtained 2',3'- bis-O-(tert-butyldimethylsilyl)-5'-deoxy-5-fluoro-N4-((pentyloxy)carbonyl) cytidine.From 2',3'-bis-O-(tert-butyldimethylsilyl)-5'-deoxy-5-fluoro-N4- ((pentyloxy)carbonyl)cytidineand tetrabutylammonium fluoride in tetrahydrofuran at room temperature for 2 hours may be prepared the product which by hydrolyses may be converted to 5-deoxy-5-fluoro-N4- ((pentyloxy)carbonyl)cytidine. Purification of the product may be carried out by silica gel chromatography (using dichloromethane:methanol = 20:1 as an eluent).

Therapeutic Function

Antitumor

Capecitabine 준비 용품 및 원자재

원자재

Pentyl chloroformate 테트라뷰틸암모늄 플루오린화물

준비 용품

Capecitabine 공급 업체

글로벌( 19)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Beijing Yibai Biotechnology Co., Ltd	0086-182-6772-3597	sales04@yibaibiotech.com	CHINA	419	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23556	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	28404	58
NewCan Biotech Limited	+86-0571-86912261 +8613735419629	sales@newcanbio.com	China	9975	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418684 +8618949823763	sales@tnjchem.com	China	25363	58
Wisdom Pharmaceutical Co., Ltd.	0086-15189180296	l_xu@wisdompharma.com	China	221	60
Nanjing Sunlida Biological Technology Co., Ltd.	025-57798810	sales@sunlidabio.com	China	3750	55
Wuhan Dahua Pharmaceutical Co., Ltd.	027-59262863 13277907145 3091977954		China	4951	58
Credit Asia Chemical Co., Ltd.	+86 (21) 61124340		China	9767	58

Capecitabine 관련 검색:

1,1′-카보닐디이미다졸 벤설프론 메틸 살리실산 메틸 플루시토신 쿠레톡심메틸 티오판산-메틸 시토신 카보닐 황화합물 5-플루오로사이티딘 브롬화 메틸 플루오린(불소) METSULFURON METHYL Methyl Carbonyl iron powder 5'-Deoxy-5-fluorocytidine Capecitabine