(4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid

(4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid C화학적 특성, 용도, 생산

Synthesis

To a stirred solution of 5-bromo-4-cyclopropyl-6-methoxy-pyrimidine in toluene and tetrahydrofuran was added triisopropyl borate at room temperature under nitrogen atmosphere. The mixture was cooled down to -70 °C. To the above mixture was slowly added n-butyl lithium dropwise at -70 °C. The resulting mixture was stirred for additional 15 min at -70 °C. The reaction was quenched with 1N HCl at -70 °C. The mixture was purified by RP-Flash, the collected fractions were combined and concentrated under reduced pressure to afford (4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid (3.5 g, 18.04 mmol, 94% yield) as a white solid.

(4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid 준비 용품 및 원자재

원자재

준비 용품

(4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10247	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	7154	58
Shanghai Neutan Pharmaceutical Co Ltd	+undefined15865876430	hujy@neutanpharma.com	China	146	58
Lianhe Aigen Pharmatech Co.,Ltd.	+86-18918657159; +undefined18918657159	sales-Aigen@lianhetech.com	China	302	58
Nanjing New Thinking Chem Co.,Ltd	+8615896017193	nanjingxinsi@163.com	China	217	58
Chemport Science Technology Shanghai) Co., Ltd.	+undefined13816004845	chen@chemport-sh.com	China	186	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Nanjing Bicbiotechnology Co., Ltd	+86-2552131256 +86-18251840740	sales@bicbiotech.com	China	6000	58
Wuhan Chiral Man Biotechnology Co., Ltd	+86-027-81610301 +86-18986082610	luanfengping@flyblueprint.com	China	196	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58