NONACTIN
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NONACTIN 속성
- 녹는점
- 147-148°
- 끓는 점
- 890.6±65.0 °C(Predicted)
- 밀도
- 1.11-1.15 g/cm3
- 저장 조건
- 2-8°C
- 용해도
- 클로로포름: 가용성10mg/mL
- 물리적 상태
- 백색 내지 황백색의 결정성 고체.
- 색상
- 흰색에서 희미한 노란색까지
- 감도
- Moisture Sensitive
- Merck
- 13,6709
- BRN
- 76434
- 안정성
- 제공된 대로 구매일로부터 1년 동안 안정적입니다. DMSO 또는 에탄올 용액은 -20°에서 최대 2개월 동안 보관할 수 있습니다.
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 안전지침서 | 22-24/25 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | RH1685000 | ||
| F 고인화성물질 | 10-21 | ||
| HS 번호 | 29321900 | ||
| 독성 | LD50 intravenous in mouse: 246mg/kg |
| 그림문자(GHS): |
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| 신호 어: | Warning | ||||||||||||||||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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NONACTIN C화학적 특성, 용도, 생산
화학적 성질
Light yellow powder용도
Nonactin is the smallest member of the macrotetrolide complex produced by a range of Streptomyces species. Originally the name, nonactin, reflected the lack of biological activity. The literature is confusing in this respect, as virtually all sources of nonactin are contaminated with small amounts of the much more active monactin. The BioAustralis nonactin has been purified to remove traces of other biologically-active macrotetrolides. Like the other macrotetrolides, nonactin is a monovalent cation ionophore with high selectivity for ammonium and potassium.생물학적 활성
Monovalent cation ionophore that displays selectivity for K + and NH 4 + (K + = NH 4 + > Na + > Mg 2+ > Li + >> Ca 2+ for nonactin-EVA sensor). Induces cation transport across artificial membranes. Also inhibits P-glycoprotein-mediated efflux of chemotherapeutic agents in multiple-drug resistant cancer cells. Antibiotic.Purification Methods
This macrotetrolide antibiotic crystallises from MeOH as colourless needles and is dried at 90o/20hours/high vacuum. [Cordaz et al. Helv Chim Acta 38 1445 1955, crystal structure: Dobler Helv Chim Acta 55 1371 1972, Gambos et al. Tetrahedron Lett 3391 1975, Beilstein 19/12 V 751.]NONACTIN 준비 용품 및 원자재
원자재
준비 용품
NONACTIN 공급 업체
글로벌( 114)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 |
1057@dideu.com | China | 2713 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 |
1026@dideu.com | China | 9126 | 58 |
| BOC Sciences | +16314854226 |
inquiry@bocsci.com | United States | 19743 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 |
info@gihichemicals.com | China | 50002 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 |
product@acmec-e.com | China | 33350 | 58 |
| Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15848 | 69 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 |
sales@heowns.com | China | 14443 | 57 |
NONACTIN 관련 검색:
메틸 3-히드록시헥사노산염 부틸 이소부틸레이트 아이소프로필 2-메틸부티르산염 아이소프로필 아이소뷰티르산 Methyl (R)-(-)-3-hydroxybuty랫드 e
Hexyl 2-methylbutyrate
propyl 2-methylpentanoate
Ethyl 6-Hydroxyhexanoate
Hexyl isobutyrate
N-PROPYL-2-METHYL BUTYRATE
AMYL-2-METHYLBUTYRATE
OCTYL ISOBUTYRATE
BUTYL-2-METHYLVALERATE
Ethyl (S)-3-hydroxybutyrate
3-HYDROXYOCTANOIC ACID
HEPTYL ISOBUTYRATE
2-(oxolan-2-yl)acetic acid
Ethyl (R)-3-hydroxybutyrate