1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE 구조식 이미지
카스 번호:
70641-51-9
상품명:
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE
동의어(영문):
EDELFOSINE;ET-18-OCH3;ET-18-OCH?;Ro 14-5243;NSC 343649;NSC 324368;SN-ET-18-OCH3;18:0-1:0 DIETHER PC;2-O-METHYL PAF C-18;innersalt,4-oxide,(+-)-hydroxide
CBNumber:
CB2768197
분자식:
C27H58NO6P
포뮬러 무게:
523.74
MOL 파일:
70641-51-9.mol
MSDS 파일:
SDS

1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE 속성

저장 조건
-20°C
용해도
에탄올: 45°C에서 15mg/mL, 가용성
물리적 상태
밀랍 같은 고체
색상
하얀색
수용성
Soluble to 20 mM in water

안전

안전지침서 22-24/25
WGK 독일 3
RTECS 번호 YK0718000

1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE C화학적 특성, 용도, 생산

용도

Edelfosine has been used to treat human lung carcinoma A549 cells and study its effects on tuftelin 1 (TUFT1) expression. It is also used to evaluate the cell growth of MCF-7/M cells.

일반 설명

Edelfosine has anti-inflammatory, anti-autoimmune, antiparasitic and anti-viral properties. It stimulates eryptosis by cell shrinkage and cell membrane scrambling.

Biochem/physiol Actions

Edelfosine is a synthetic alkyl-lisophospholipid with anti-tumor activity. The compound induces apoptosis in a variety of cancer cells. Edelfosine accumulates in the cell membrane, where it alters lipid composition and induces the co-clustering of lipid rafts and Fas/CD95 death receptor.

1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE 준비 용품 및 원자재

원자재

준비 용품


1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE 공급 업체

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