(2S)-[(2S)-[(2R)-AMINO-3-MERCAPTO]-PROPYLAMINO-(3S)-METHYL]PENTYLOXY-3-PHENYLPROPIONYL-메티오닌설폰이소프로필에스테르비스염산염

(2S)-[(2S)-[(2R)-AMINO-3-MERCAPTO]-PROPYLAMINO-(3S)-METHYL]PENTYLOXY-3-PHENYLPROPIONYL-메티오닌설폰이소프로필에스테르비스염산염
(2S)-[(2S)-[(2R)-AMINO-3-MERCAPTO]-PROPYLAMINO-(3S)-METHYL]PENTYLOXY-3-PHENYLPROPIONYL-메티오닌설폰이소프로필에스테르비스염산염 구조식 이미지
카스 번호:
1177806-11-9
한글명:
(2S)-[(2S)-[(2R)-AMINO-3-MERCAPTO]-PROPYLAMINO-(3S)-METHYL]PENTYLOXY-3-PHENYLPROPIONYL-메티오닌설폰이소프로필에스테르비스염산염
동의어(한글):
(2S)-[(2S)-[(2R)-AMINO-3-MERCAPTO]-PROPYLAMINO-(3S)-METHYL]PENTYLOXY-3-PHENYLPROPIONYL-메티오닌설폰이소프로필에스테르비스염산염
상품명:
L-744,832
동의어(영문):
L-744832;L-744,832;L-744,832 Dihydrochloride;L-744,832 - CAS 1177806-11-9 - Calbiochem;(2S)-[(2S)-[(2R)-AMINO-3-MERCAPTO]-PROPYLAMINO-(3S)-METHYL]PENTYLOXY-3-PHENYLPROPIONYL-METHIONINE SULFONE ISOPROPYL ESTER BIS HYDRCHLORIDE;(2S)-[(2S)-[(2R)-Amino-3-mercapto]-propylamino-(3S)-methyl]pentyloxy-3-phenylpropionyl-methionine Sulfone Isopropyl Ester Bis Hydrchloride,
CBNumber:
CB3188792
분자식:
C26H47Cl2N3O6S2
포뮬러 무게:
632.7
MOL 파일:
Mol file
MSDS 파일:
SDS

(2S)-[(2S)-[(2R)-AMINO-3-MERCAPTO]-PROPYLAMINO-(3S)-METHYL]PENTYLOXY-3-PHENYLPROPIONYL-메티오닌설폰이소프로필에스테르비스염산염 속성

녹는점
165-168°C
저장 조건
-20°C Freezer
용해도
DMSO(약간 용해됨), 메탄올(약간 용해됨)
물리적 상태
흰색 고체
색상
하얀색

안전

(2S)-[(2S)-[(2R)-AMINO-3-MERCAPTO]-PROPYLAMINO-(3S)-METHYL]PENTYLOXY-3-PHENYLPROPIONYL-메티오닌설폰이소프로필에스테르비스염산염 C화학적 특성, 용도, 생산

화학적 성질

L-744,832 is White Cyrstalline Solid

용도

L-744,832 is ras farnesyltransferase inhibitor. Induces tumor regression in transgenic mice with multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis. Induces p21 expressoin and arrests cells at G1. Causes enhanced mitotic

일반 설명

A cell-permeable potent and selective thiol-containing peptidomimetic farnesyltransferase (FTase) inhibitor with anti-tumor properties. Rapidly blocks p70S6K activation and DNA synthesis and promotes apoptosis in transgenic mice. Induces p21 expression and cell cycle arrest in the G1 phase. Displays synergistic effect with paclitaxel and epothilones in inhibiting tumor growth. Also mimics many of the effects of Rapamycin (Cat. No. 553210) and may be effective against tumors that exhibit inappropriate activation of the mTOR/p70S6K pathway.

(2S)-[(2S)-[(2R)-AMINO-3-MERCAPTO]-PROPYLAMINO-(3S)-METHYL]PENTYLOXY-3-PHENYLPROPIONYL-메티오닌설폰이소프로필에스테르비스염산염 준비 용품 및 원자재

원자재

준비 용품


(2S)-[(2S)-[(2R)-AMINO-3-MERCAPTO]-PROPYLAMINO-(3S)-METHYL]PENTYLOXY-3-PHENYLPROPIONYL-메티오닌설폰이소프로필에스테르비스염산염 공급 업체

글로벌( 33)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Alpha Biopharmaceuticals Co., Ltd
+86-411-39042497 +8613921981412
sales@alphabiopharm.com China 886 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439
sales@nextpeptide.com China 19915 58
Aladdin Scientific
+1-833-552-7181
sales@aladdinsci.com United States 52927 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
3bsc@sina.com China 15848 69
Alabiochem Tech.Co., Ltd. 0512-58900862 400-0707518
sales@alabiochem.com China 995 59
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32344 50
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9709 58
Alabiotech Inc. 001-619-354-5251
sales@alabiotech-e.com United States 972 60

(2S)-[(2S)-[(2R)-AMINO-3-MERCAPTO]-PROPYLAMINO-(3S)-METHYL]PENTYLOXY-3-PHENYLPROPIONYL-메티오닌설폰이소프로필에스테르비스염산염 관련 검색:

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