에틸 피루브산
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에틸 피루브산 속성
- 녹는점
- -58 °C
- 끓는 점
- 144 °C (lit.)
- 밀도
- 1.045 g/mL at 25 °C (lit.)
- 증기압
- 2.36hPa at 25℃
- 굴절률
- n
20/D 1.404(lit.)
- 인화점
- 114 °F
- 저장 조건
- Store at +2°C to +8°C.
- 용해도
- 10g/L
- 물리적 상태
- 액체
- 색상
- 맑은 연한 노란색
- 냄새
- 디프로필렌 글리콜 중 10.00%. 에테르 과일 같은 달콤한 샤프 럼 야채 카라멜
- ?? ??
- 미묘한
- 수용성
- 물, 에탄올, 에테르와 혼합 가능.
- Merck
- 14,8021
- JECFA Number
- 938
- BRN
- 1071466
- 안정성
- 휘발성 물질
- InChIKey
- XXRCUYVCPSWGCC-UHFFFAOYSA-N
- LogP
- 0.435 at 22.5℃
- CAS 데이터베이스
- 617-35-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi,F | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 10 | ||
| 안전지침서 | 16 | ||
| 유엔번호(UN No.) | UN 3272 3/PG 3 | ||
| WGK 독일 | 3 | ||
| 위험 참고 사항 | Flammable/Irritant | ||
| TSCA | Yes | ||
| 위험 등급 | 3 | ||
| 포장분류 | III | ||
| HS 번호 | 29183000 | ||
| 독성 | LD50 orally in Rabbit: > 2000 mg/kg LD50 dermal Rat > 2000 mg/kg | ||
| 기존화학 물질 | KE-27650 |
에틸 피루브산 C화학적 특성, 용도, 생산
화학적 성질
Ethyl pyruvate has a vegetable, caramel odor.출처
Reported found in Parmesan cheese, cognac, grape wines, cocoa and mushrooms.용도
Ethyl pyruvate (EP) has demonstrated neuroprotective effects against acute brain injury through its anti-inflammatory action.제조 방법
By direct esterification of pyruvic acid with absolute ethyl alcohol at the boil and subsequent vacuum distillation; by esterification via oxidation of vapors of ethyl lactate in the presence of V2O5 at 155°C일반 설명
Ethyl pyruvate is a volatile aliphatic ester of the pyruvate metabolite. It is present as a food additive/odor-active component in various food and beverage products. It is also used as an inhibitory odorant to repel the insects from human proximity.Purification Methods
Shake the ester with 10mL portions of saturated aqueous CaCl2 solution (removes ethyl acetate) and the organic layer is removed by centrifugation, decantation and filtration, and is distilled under reduced pressure. Purification of small quantities is carried out via the bisulfite adduct: the ester (2.2mL) is shaken with saturated NaHSO3 (3.6mL), chilled in a freezing mixture when crystals separate rapidly (particularly if seeded). After 5minutes EtOH (10mL) is added and the crystals are filtered off, washed with EtOH and Et2O and dried. Yield ca 3g of bisulfite adduct. Then treat the adduct (16g) with saturated aqueous MgSO4 (32mL) and 40% formaldehyde (5mL) and shake, whereby the ester separates as an oil which is extracted with Et2O. The extract is dried (MgSO4), filtered, evaporated and the residue is distilled (b 56o/20mm), and then redistilled (b 147.5o/750mm) to give 5.5g of pure ester. [Cornforth Org Synth Coll Vol IV 467 1963, Beilstein 3 IV 1513.]에틸 피루브산 준비 용품 및 원자재
원자재
준비 용품
5-Bromoindole-2-carboxylic acid
5-TERT-BUTYL-1H-INDOLE-2-CARBOXYLIC ACID ETHYL ESTER
2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carbonitrile
5-Aminoindole
1-METHYL-5-NITRO-1H-INDOLE
2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxamide
(2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)methanamine
5-Nitroindole
Ethyl 2-(4-hydroxypiperidin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylate
Ethyl 2-(4-(ethoxycarbonyl)piperidin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylate
Ethyl 2-(4-(hydroxymethyl)piperidin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylate
Ethyl 5-nitroindole-2-carboxylate
(2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)methanol
5-BROMO-1H-INDOLE-2-CARBALDEHYDE
Ethyl 5-chloro-2-indolecarboxylate
5-Chloroindole-2-carboxylic acid
5-CHLORO-1H-INDOLE-2-CARBALDEHYDE
피루브산
ETHYL 1,2,3-THIADIAZOLE-4-CARBOXYLATE
2-(4-Hydroxypiperidin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxamide
Ethyl 2-(4-methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylate
5-amino-1H-Indole-2-carboxylic acid ethyl ester
2-(4-(Hydroxymethyl)piperidin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxamide
IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID
2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carbaldehyde
ETHYL 5-AMINO-1H-INDOLE-2-CARBOXYLATE
3-METHYL-2-QUINOXALINOL
1-(4-(Hydroxymethyl)-6-(trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol
2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylic acid
2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidin-4-amine
Ethyl 5-Bromoindole-2-carboxylate
ETHYL 4,6-DICHLORO-3-FORMYL-1H-INDOLE-2-CARBOXYLATE
IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER
(1,2,3-THIADIAZOL-4-YL)METHANOL
(1-(4-(Hydroxymethyl)-6-(trifluoromethyl)pyrimidin-2-yl)piperidin-4-yl)methanol
(5-BROMO-1H-INDOL-2-YL)METHANOL
에틸 피루브산 공급 업체
글로벌( 592)공급 업체
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| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
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| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 |
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| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
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| Shaanxi Franta Biotechnology Co., Ltd | +86-13082019107 +86-13082019107 |
admin@flanderff.com | China | 229 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 |
sales02@airuikechemical.com | China | 994 | 58 |
| CONTIDE BIOTECH CO.,LTD | +85253358525 |
xena@healthtide-api.com | China | 519 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |