페놀,2-메톡시-5-[[[(1E)-2-(2,4,6-트리메톡시페닐)에테닐]술포닐]메틸]-,1-(인산이수소)
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페놀,2-메톡시-5-[[[(1E)-2-(2,4,6-트리메톡시페닐)에테닐]술포닐]메틸]-,1-(인산이수소) 속성
- 저장 조건
- Sealed in dry,Room Temperature
- 용해도
- DMF: 30 mg/ml; DMSO: 30 mg/ml
- 물리적 상태
- 결정성 고체
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
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신호 어: | Warning | |||||||||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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페놀,2-메톡시-5-[[[(1E)-2-(2,4,6-트리메톡시페닐)에테닐]술포닐]메틸]-,1-(인산이수소) C화학적 특성, 용도, 생산
개요
Briciclib is a water soluble derivative of ON 013100, a small molecule that binds to and inhibits eukaryotic translation initiation factor 4E (eIF4E). Briciclib inhibits proliferation of JEKO-1 and Mino mantle cell leukemia (MCL), MCF-7 and MDA-MB-231 breast, AGS gastric, and OE19, OE33, and LFO-1 esophageal cancer cell lines with GI50 values ranging from 9.8 to 12.2 nM. It reduces expression of cyclin D1 and c-Myc, markers of eIF4E activity, in breast and MCL cancer cell lines in a dose-dependent manner. Briciclib also induces expression of the pro-apoptotic proteins p53 and cleaved caspase-3.페놀,2-메톡시-5-[[[(1E)-2-(2,4,6-트리메톡시페닐)에테닐]술포닐]메틸]-,1-(인산이수소) 준비 용품 및 원자재
원자재
준비 용품
페놀,2-메톡시-5-[[[(1E)-2-(2,4,6-트리메톡시페닐)에테닐]술포닐]메틸]-,1-(인산이수소) 공급 업체
글로벌( 59)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32715 | 60 |
Career Henan Chemica Co | +86-0371-86658258 15093356674; |
laboratory@coreychem.com | China | 30255 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 |
sales@molcore.com | China | 49739 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 |
trendseenbio@gmail.com | China | 11681 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
MQ (shanghai) Pharmaceuticals Co., Ltd. | 13761635123 |
1014988033@qq.com | China | 4986 | 55 |
Shanghai Boyle Chemical Co., Ltd. | |
sales@boylechem.com | China | 2923 | 55 |
Haoyuan Chemexpress Co., Ltd. | 021-58950125 |
info@chemexpress.com | China | 7553 | 61 |