Pranlukast
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Pranlukast 속성
- 녹는점
- 236-238°C
- 밀도
- 1.374±0.06 g/cm3(Predicted)
- 저장 조건
- Sealed in dry,Store in freezer, under -20°C
- 용해도
- DMSO에 용해됨(최대 25mg/ml)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 4.96±0.10(Predicted)
- 색상
- 하얀색
- Merck
- 14,7710
- 안정성
- 제공된 대로 구매일로부터 1년 동안 안정적입니다. DMSO의 솔루션은 -20°C에서 최대 1개월 동안 보관할 수 있습니다.
- CAS 데이터베이스
- 103177-37-3(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | F,C | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 11-34 | ||
| 안전지침서 | 16-26-36/37/39-45 | ||
| RTECS 번호 | CV5647500 | ||
| HS 번호 | 2934.99.4400 | ||
| 독성 | LD50 in male mice (mg/kg): >1000 i.v. (Toda) |
Pranlukast C화학적 특성, 용도, 생산
개요
Pranlukast, a novel chromone derivative, was introduced in Japan for the treatment of bronchial asthma and allergic diseases. Pranlukast is a highly potent, selective and competitive antagonist of peptidoleukotrienes with high affinity for the LTD4 receptor. In patients with bronchial asthma, pranlukast was reported to induce significant improvement in both immediate and late asthmatic response induced by antigen. Pranlukast is also being evaluated clinically for the treatment of perennial allergic rhinitis, pediatric asthma, and cutaneous pruritus in dialysis patients. The therapeutic potential of pranlukast in managing irritable bowel syndrome has been suggested.화학적 성질
Off-white solid용도
Labeled Pranlukast, intended for use as an internal standard for the quantification of Pranlukast by GC- or LC-mass spectrometry.생물학적 활성
Selective cysteinyl leukotriene receptor 1 (CysLT 1 ) antagonist (IC 50 values are ~ 4-7 and 3620 nM for CysLT 1 and CysLT 2 respectively). Inhibits contraction of airway smooth muscle, microvascular leakage into airways and eosinophil infiltration. Can decrease symptoms of bronchial asthma.Pranlukast 준비 용품 및 원자재
원자재
준비 용품
Pranlukast 공급 업체
글로벌( 271)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 |
admin@hbouhuang.com | China | 2991 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9346 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8823 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 |
overseasales1@yongstandards.com | United States | 14336 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49390 | 58 |
Pranlukast 관련 검색:
FLURBI프로FEN 뷰틸 페닐 에터
Kasumi-1
NRK-49F
NEC8
Haloperidol
Zafirlukast
Montelukast sodium
8-[4(4-phenylbutoxy)benzoyl]amino-2-(5-tetrazolyl)-4-oxo-4H-1-benzopyran
OCI-LY10 (diffuse large B cell lymphoma cells)
MMVECS mouse cardiac microvascular endothelial cells
JG mouse paraglomerular cells
Pranlukast
3-Amino-2-hydroxyacetophenone
3''-ACETYL-2''-HYDROXY-4-(4-PHENYLBUTOXY)BENZANILIDE
4-ETHOXY-N-PHENYLBENZAMIDE
4-ethoxy-N-(2-methoxyphenyl)benzamide
4-METHOXY-N-(2-METHOXYPHENYL)BENZAMIDE