2-METHYLISONICOTINALDEHYDE

2-METHYLISONICOTINALDEHYDE 구조식 이미지
카스 번호:
63875-01-4
상품명:
2-METHYLISONICOTINALDEHYDE
동의어(영문):
2-METHYL-4-FORMYLPYRIDINE;4-FORMYL-2-METHYLPYRIDINE;2-METHYLISONICOTINALDEHYDE;2-Methylisonicotinaldehyde 95%;2-Methyl-4-pyridinecarbaldehyde;2-METHYLPYRIDINE-4-CARBALDEHYDE;2-METHYLPYRIDINE-4-CARBOXALDEHYDE;2-Methyl-4-Pyridinecarboxaldehyde;4-Pyridinecarboxaldehyde,2-Methyl-;3-forMyl-2-Methylpyridine-4-carboxylic acid
CBNumber:
CB4126555
분자식:
C7H7NO
포뮬러 무게:
121.14
MOL 파일:
63875-01-4.mol

2-METHYLISONICOTINALDEHYDE 속성

녹는점
83 °C
끓는 점
53-54 °C(Press: 0.5 Torr)
밀도
1.095±0.06 g/cm3(Predicted)
저장 조건
under inert gas (nitrogen or Argon) at 2-8°C
산도 계수 (pKa)
3.98±0.10(Predicted)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
HS 번호 2933399990
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

2-METHYLISONICOTINALDEHYDE C화학적 특성, 용도, 생산

용도

2-Methylisonicotinaldehyde belongs to the pyridine group of compounds and is used in the preparation of benzimidazoles and related analogues as sirtuin modulators and in the synthesis of other organic compounds.

Synthesis

2-Methylisonicotinaldehyde is synthesised using methanol as raw material by chemical reaction. The specific synthesis steps are as follows:
A solution of N,N-dimethyl-2-(2-methyl-4-pyridyl)ethenamine (6.4 g, 39 mmol) in methanol (25 ml) was added dropwise to a mixture of sodium periodate (25.2 g, 117 mmol) and methanol (25 ml) at room temperature.. The mixture was stirred at the same temperature for 1 hr.. The precipitates were filtered off, and the filtrate was concentrated.. The residue was combined with water and extracted with ethyl acetate.. The organic layer was washed with saturated brine and dried over magnesium sulfate.. The solvent was evaporated to give the titled compound (3.7 g, 78 percent).1H-NMR (CDCl3) δ: 2.68 (3H, s), 7.51 (1H, d, J = 4.9 Hz), 7.56 (1H, s), 8.76 (1H, d, J = 4.9 Hz), 10.05 (1H, s).
2-METHYLISONICOTINALDEHYDE synthesis

2-METHYLISONICOTINALDEHYDE 준비 용품 및 원자재

원자재

준비 용품


2-METHYLISONICOTINALDEHYDE 공급 업체

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