cangrelor테트라소듐

cangrelor테트라소듐
cangrelor테트라소듐 구조식 이미지
카스 번호:
163706-36-3
한글명:
cangrelor테트라소듐
동의어(한글):
cangrelor테트라소듐
상품명:
cangrelor tetrasodium
동의어(영문):
CS-1027;angrelor tetrasodium;cangrelor tetrasodium;Cangrelor Tetrasodium Salt;AR-C 69931 Tetrasodium Salt;Cangrelor tetrasodium salt >=98% (HPLC);tetrasodium 5'-O-[({[dichloro(phosphonato)methyl]phosphinato...;N-[2-(Methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]adenosine-5'-O-(β,γ-dichloromethylene)triphosphate tetrasodium salt;tetrasodium 5'-O-[({[dichloro(phosphonato)methyl]phosphinato}oxy)phosphinato]-N-[2-(methylsulfanyl)ethyl]-2-[(3,3,3-trifluoropropyl)sulfanyl]adenosine;(Dichloro((((((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-((2-(methylthio)ethyl)amino)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)methyl)phosphonic acid tetrasodium salt
CBNumber:
CB43040494
분자식:
C17H21Cl2F3N5Na4O12P3S2
포뮬러 무게:
864.2865126
MOL 파일:
163706-36-3.mol
MSDS 파일:
SDS

cangrelor테트라소듐 속성

저장 조건
4°C, away from moisture and light
용해도
DMSO:100.0(Max Conc. mg/mL);115.7(Max Conc. mM)
물리적 상태
고체
수용성
물에 100mM까지 용해됨
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 GHS hazard pictograms P264, P270, P301+P312, P330, P501
예방조치문구:
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
0
2 0

cangrelor테트라소듐 C화학적 특성, 용도, 생산

개요

Cangrelor tetrasodium is a direct purinergic platelet receptor (P2Y12) inhibitor that blocks ADP-induced platelet activation and aggregation. The drug, which was developed by The Medicine Company, binds reversibly to the P2Y12 receptor, preventing further signaling and platelet activation. Cangrelor, which was approved in June 2015 by the FDA, is indicated as an adjunct to percutaneous coronary intervention for reducing the risk of periprocedural myocardial infarction, repeat coronary revascularization, and stent thrombosis in patients who have not been treated with a P2Y12 platelet inhibitor and are not being given a glycoprotein IIb/IIIa inhibitor. The most common side effect observed with the drug was bleeding.

용도

Antiplatelet agent.

정의

ChEBI: An organic sodium salt that is the tetrasodium salt of cangrelor. Used as an intravenous antiplatelet drug that prevents formation of harmful blood clots in the coronary arteries.

cangrelor테트라소듐 준비 용품 및 원자재

원자재

준비 용품


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