디프로필 케톤 C화학적 특성, 용도, 생산
개요
4-Heptanone has a penetrating odor and burning taste. It is prepared by passing butyric acid over a wood coal at 425°C and then
over cerium oxide at 500°C or over thorium oxide; also over
manganese oxide at 400 - 425°C.
화학적 성질
4-Heptanone has a penetrating odor and burning taste.
출처
Reported found in apple juice, papaya, pear, cabbage, baked potato, roasted peanut, chicken fat, coffee, bachang (Mangifera foetida L ) and rooibus tea (Aspalathius linearis)
용도
4-Heptanone is used as a solvent for nitrocellulose as well as in organic synthesis. It is involved in the preparation of flavorings. It is used as an intermediate in the synthesis of active pharmaceutical ingredients. Further, it is used in paints and coatings.
제조 방법
By passing butyric acid over wood coal at 425°C and then over cerium oxide at 500°C or over thorium oxide; also over manganese oxide at 400 to 425°C.
일반 설명
A colorless liquid with a pleasant odor. Insoluble in water and less dense than water. Flash point 120°F. Toxic by inhalation. A skin irritant. Used to make flavorings and as a solvent.
공기와 물의 반응
Flammable. Insoluble in water.
반응 프로필
4-Heptanone is incompatible with the following: Oxidizers .
건강위험
Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
화재위험
Combustible liquid; flash point (closed cup)
49°C (120°F); vapor density 3.9 (air = 1);
vapor pressure 5.2 torr at 20°C (68°F); fireextinguishing agent: “alcohol” foam or water
spray. DPK forms explosive mixtures with
air; LEL and UEL values have not been
reported. It is incompatible with strong acids,
alkalies, and oxidizers.
.
Safety Profile
and skin contact. A
skin and eye irritant. Flammable liquid when
exposed to heat or flame; can react with
oxidizing materials. To fight fire, use CO2,
dry chemical, alcohol foam, fog, and mist.
When heated to decomposition it emitsacrid smoke and fumes. See also
KETONES.
신진 대사
When 950 mg methyl amyl ketone/kg body weight was administered orally to rabbits, 40% was excreted as heptyl-2-glucuronide, and traces of the unchanged ketone were also found in the urine (Kamil, Smith & Williams, 1953). 2-Heptanone (methyl amyl ketone) was identified as being among the approximately 300 compounds present in the volatile constituents of urine from male and female subjects (Zlatkis & Liebich, 1971).
Purification Methods
Dry 4-pentanone with CaSO4, then distil it from P2O5 under nitrogen. [Beilstein 1 IV 3323.]
폐기물 처리
DPK is burned in a chemical incineratorequipped with an afterburner and scrubber.
디프로필 케톤 준비 용품 및 원자재
원자재
준비 용품
