Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
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Ethyl (R)-(-)-4-cyano-3-hydroxybutyate 속성
- 알파
- -5 º (neat)
- 끓는 점
- 270 °C(lit.)
- 밀도
- 1.114 g/mL at 25 °C(lit.)
- 굴절률
- n
20/D 1.448(lit.)
- 인화점
- >230 °F
- 저장 조건
- 2-8°C
- 용해도
- 클로로포름(난용성), DMSO (약간 용해됨), 메탄올 (약간 용해됨)
- 물리적 상태
- 액체
- 산도 계수 (pKa)
- 13.03±0.20(Predicted)
- 색상
- 무색~황색
- Specific Gravity
- 1.114
- optical activity
- [α]25/D 5°, neat
- BRN
- 5328715
- InChIKey
- LOQFROBMBSKWQY-ZCFIWIBFSA-N
- CAS 데이터베이스
- 141942-85-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
Ethyl (R)-(-)-4-cyano-3-hydroxybutyate C화학적 특성, 용도, 생산
화학적 성질
yellow liquid주요 응용
Hydroxyglutaryl coenzyme A (HMG-CoA) reductase inhibitors are a new class of lipid-lowering drugs, and they have a market share of more than 10 billion US dollars in the current pharmaceutical field. They can selectively inhibit the rate-limiting enzyme HMG-CoA reductase in cholesterol synthesis in the liver, reduce liver lipoprotein production, and increase the expression of low-density lipoprotein (LDL) cholesterol receptors, thereby reducing plasma cholesterol levels. They can also significantly reduce very low-density lipoprotein (VLDL) and triglycerides, and increase anti-atherosclerotic high-density protein (HDL), preventing atherosclerosis and coronary heart disease.Ethyl (R)-(-)-4-cyano-3-hydroxybutyate is an important intermediate for the synthesis of HMG-CoA reductase inhibitors. If it is used as a raw material, synthetic atorvastatin is mainly used for the treatment of hypercholesterolemia and mixed hyperlipidemia, coronary heart disease and stroke.
Ethyl (R)-(-)-4-cyano-3-hydroxybutyate 준비 용품 및 원자재
원자재
Butanoic acid, 4-cyano-3-hydroxy-, (3R)-
Ethyl 4-bromo-3-hydroxybutyrate
사이안화 나트륨
에틸알코올
4-클로로아세트 초산에틸
준비 용품
Ethyl (R)-(-)-4-cyano-3-hydroxybutyate 공급 업체
글로벌( 425)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Jiangxi Sunway Chemical Co., Ltd. | +86-0794-5259909 +8615888611133 |
dave@jxswchem.com | China | 22 | 58 |
| Jiangxi Sunway Chemical Co., Ltd. | +86-0794-5259909 +8615888611133 |
dave@jxswchem.com | China | 22 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
| Hebei Dangtong Import and export Co LTD | +8615632927689 |
admin@hbdangtong.com | China | 991 | 58 |
| Hangzhou ICH Biofarm Co., Ltd | +undefined8613073685410 |
sales@ichemie.com | China | 985 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 |
sales03@chemcn.cn | China | 951 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15933 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |