디드로제스테론
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디드로제스테론 속성
- 녹는점
- 168-173°C
- 알파
- D25 -484.5° (chloroform)
- 끓는 점
- 392.36°C (rough estimate)
- 밀도
- 1.0697 (rough estimate)
- 굴절률
- 1.4900 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- 물에는 거의 녹지 않으며, 아세톤에는 녹고, 에탄올에는 거의 녹지 않습니다(96%).
- 색상
- 흰색에서 밝은 노란색
- InChI
- InChI=1/C21H28O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h4-5,12,16-19H,6-11H2,1-3H3/t16-,17+,18-,19+,20+,21+/s3
- InChIKey
- JGMOKGBVKVMRFX-HQZYFCCVSA-N
- SMILES
- C[C@@]12CCC(=O)C=C1C=C[C@@]1([H])[C@]3([H])CC[C@H](C(=O)C)[C@@]3(C)CC[C@@]21[H] |&1:1,10,12,16,20,24,r|
- CAS 데이터베이스
- 152-62-5(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 유엔번호(UN No.) | UN 3077 9 / PGIII | ||
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| 유해 물질 데이터 | 152-62-5(Hazardous Substances Data) | ||
| 독성 | LD50 oral in rat: > 4600mg/kg |
| 그림문자(GHS): |
 
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| 신호 어: | Danger | |||||||||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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디드로제스테론 MSDS
17-Acetyl-10,13-dimethyl-1,2,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one
디드로제스테론 C화학적 특성, 용도, 생산
개요
Dydrogesterone is a synthetic progestogen that has no estrogenic, androgenic, glucocorticoid, or anabolic effects, although it is an agonist of progesterone receptors (EC50 = 12.3 nM) and an antagonist of androgen, mineralocorticoid, and glucocorticoid receptors (IC50s = 28.6, 82.7, and 363 nM, respectively). Dydrogesterone protects against sound stress-induced abortion in mice when administered at a dose of 1.25 mg per animal prior to the stressor on day five of pregnancy. Formulations containing dydrogesterone have been used in hormone replacement therapy, in the treatment of menstrual disorders, and to prevent miscarriage.화학적 성질
Light Yellow Solid용도
A synthetic progestin largely used in hormone therapy, on the central nervous system by studying two markers of the neuroendocrine function: the neurosteroid allopregnanolone and the opioid .beta.-endorphin. Progestogen.주요 응용
Dydrogesterone is a synthetic progestin. Dydrogesterone alone or in combination with estrogen to endothelial cells results in neutral effects on NO synthesis and on the activity and expression of eNOS.Synthesis
Dissolving progesterone, and carrying out photochemical reaction to obtain 9 beta, 10 alpha-pregn-4-ene-3, 20-diketone; mixing the 9 beta, 10 alpha-pregn-4-ene-3, 20-dione, an organic solvent and a benzoquinone oxidant, and carrying out dehydrogenation oxidation reaction to obtain dydrogesterone.디드로제스테론 준비 용품 및 원자재
원자재
준비 용품
디드로제스테론 공급 업체
글로벌( 290)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Pharmaceuticals Group Corp., Ltd. | +8613004379774 |
wu@jiaerke.com | China | 33 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 +86-13986145403 |
info@fortunachem.com | China | 5988 | 58 |
| Wuhan Han Sheng New Material Technology Co.，Ltd | +8617798174412 |
admin01@hsnm.com.cn | China | 2118 | 58 |
| Biopole Pharmatech Co., Ltd. | +8615151475053 |
biopole@163.com | China | 37 | 58 |
| Nanjing Huazhou New Material Co., Ltd. | +8618913378169 |
howard.wu@chinaredsun.com | China | 40 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5993 | 58 |
| Dorne Chemical Technology co. LTD | +86-13583358881 +86-18560316533 |
Ethan@dornechem.com | China | 294 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 |
admin@guyunchem.com | China | 616 | 58 |
| Shandong Hanjiang Chemical Co., Ltd | +86-0533-2066820 +8618369939125 |
hanson@sdhanjiang.com | China | 1527 | 58 |
| Hebei Kangcang new material Technology Co., LTD | +8619133911216 |
fanfan@kangcang.com.cn | China | 340 | 58 |