Fasudil hydrochloride
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Fasudil hydrochloride 속성
- 녹는점
- 220.5°; mp 219.3° (Shirotani)
- 저장 조건
- Inert atmosphere,Store in freezer, under -20°C
- 용해도
- H2O: >200 mg/mL
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 하얀색
- 수용성
- 물과 디메틸설폭사이드에 용해됩니다. 에탄올에 불용성.
- Merck
- 14,3942
- 안정성
- 제공된 대로 구매일로부터 2년 동안 안정적입니다. DMSO 또는 증류수 용액은 -20°에서 최대 1개월 동안 보관할 수 있습니다.
- InChI
- InChI=1S/C14H17N3O2S.2ClH/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14;;/h1,3-5,7,11,15H,2,6,8-10H2;2*1H
- InChIKey
- LFVPBERIVUNMGV-UHFFFAOYSA-N
- SMILES
- N1(S(C2=CC=CC3=C2C=CN=C3)(=O)=O)CCCNCC1.[H]Cl.[H]Cl
- CAS 데이터베이스
- 105628-07-7(CAS DataBase Reference)
Fasudil hydrochloride C화학적 특성, 용도, 생산
개요
Fasudil hydrochloride, a novel calcium antagonistic vasodilator, was marketed for the treatment of cerebral vasospasm following subarachnoid hemorrhage (SAH). Fasudil is also a potent inhibitor of myosin light chain kinase and protein kinase C. In contrast to other calcium channel blockers, which regulate the influx of calcium ions through the cell membrane but not involved in the intracellular regulatory mechanism of the calcium, fasudil was suggested to have an intracellular mode of action in relaxing vascular smooth muscle. In patients with neurological deficits due to vasospasm, fasudil decreased the occurrence of angiographic severe and symptomatic vasospasm and cerebral infarction without decreasing systemic blood pressure. Fasudil is reportedly in clinical trials for acute ischemic stroke, sequelae of cerebral vascular diseases and angina pectoris.용도
vasodilator, potent Rho-kinase inhibitorFasudil hydrochloride 준비 용품 및 원자재
원자재
5-이소퀴놀린술폰산
FASUDIL
Isoquinoline-5-sulphonyl chloride hydrochloride
5-Chloro-1,3-dimethoxybenzene
호모피페라진
준비 용품
Fasudil hydrochloride 공급 업체
글로벌( 455)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd. | +86-029-86185165 +8618629664246 |
guoyuan@eastchinapharm.com | China | 1615 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12470 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 6001 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 16799 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 |
sarah@tnjone.com | China | 1072 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 |
sales@frappschem.com | China | 885 | 50 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15965 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Fasudil hydrochloride 관련 검색:
이소퀴놀린 트리에틸아민 하이드로클로라이드 피리딘 하이드로클로라이드 D-글루코사민 1,8-디아자비사이클로[5.4.0]운덴센-7
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