아미세틴-A

아미세틴-A
아미세틴-A 구조식 이미지
카스 번호:
17650-86-1
한글명:
아미세틴-A
동의어(한글):
아미세틴-A
상품명:
Amicetin-A
동의어(영문):
amicetin;Amicetin-A;Amomycin A;Benzamide, 4-[[(2S)-2-amino-3-hydroxy-2-methyl-1-oxopropyl]amino]-N-[1-[(2R,5S,6R)-5-[[4,6-dideoxy-4-(dimethylamino)-α-D-glucopyranosyl]oxy]tetrahydro-6-methyl-2H-pyran-2-yl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-
CBNumber:
CB61244964
분자식:
C29H42N6O9
포뮬러 무게:
618.68
MOL 파일:
17650-86-1.mol

아미세틴-A 속성

녹는점
244-245°
알파
D24 +116.5° (c = 0.5 in 0.1N HCl)
끓는 점
660.6°C (rough estimate)
밀도
1.2721 (rough estimate)
굴절률
1.6400 (estimate)
산도 계수 (pKa)
pKa = 10.4, 7.0(at 25℃)

안전

독성 LD50 of citrate complex, pH 6 (mg/kg) in mice: ~90 i.v., 600-700 s.c.; in rats: ~200 i.v., ~600 s.c. (DeBoer)

아미세틴-A C화학적 특성, 용도, 생산

효소 저해제

These pyrimidine-containing glycoside antibiotic (FWAmicetin-A = 617.69 g/mol (free base); CAS 17650-86-1; FWAmicetin-B = 532.59 g/mol (free base)) from Streptomyces vinaceus-drappus and S. fasciculatus inhibits protein biosynthesis, exerting its bacteriostatic most potently on Grampositive bacteria. Amicetin B, also called plicacetin, was isolated from Streptomyces plicatus and has the identical structure minus the amethylseryl residue. It is weaker in action compared to amicetin A. Target(s): peptidyltransferase; peptidyl-tRNA hydrolase, or aminoacyl-tRNA hydrolase; ribonuclease P; protein biosynthesis.

아미세틴-A 준비 용품 및 원자재

원자재

준비 용품


아미세틴-A 공급 업체

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