SJA6017
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SJA6017 속성
- 밀도
- 1.185±0.06 g/cm3(Predicted)
- 저장 조건
- Store at -20°C
- 용해도
- DMSO: 5 mg/ml
- 물리적 상태
- A lyophilized solid
- 산도 계수 (pKa)
- 9.04±0.50(Predicted)
안전
SJA6017 C화학적 특성, 용도, 생산
개요
Calpain inhibitor VI is an inhibitor of the calcium-dependent cysteine proteases μ-calpain (calpain-1; IC50 = 7.5 nM) and m-calpain (calpain-2; IC50 = 78 nM). It also inhibits cathepsins B and L (IC50s = 15 and 1.6 nM, respectively). It is selective for these calpains and cathepsins over other cysteine and serine proteases, factor VIIa, factor Xa, trypsin, chymotrypsin, and proteasome. In an in vitro porcine model of cataract, calpain inhibitor VI decreases the degree of cataract by 40% when used at a concentration of 0.8 μM. It also prevents cataract formation induced by selenite in rats when administered at a dose of 100 mg/kg for 4 days. Calpain inhibitor VI improves functional outcome and reduces apoptotic cell death in a rat model of spinal cord injury.SJA6017 준비 용품 및 원자재
원자재
준비 용품
SJA6017 공급 업체
글로벌( 41)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Alpha Biopharmaceuticals Co., Ltd | +86-411-39042497 +8613921981412 |
sales@alphabiopharm.com | China | 886 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 |
sales@nextpeptide.com | China | 19915 | 58 |
Nanjing TGpeptide | +86-13347807150 +86-13347807150 |
support@tgpeptide.com | China | 3279 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
Alabiochem Tech.Co., Ltd. | 0512-58900862 400-0707518 |
sales@alabiochem.com | China | 996 | 59 |
GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 |
ymbetter@glbiochem.com | China | 9981 | 64 |
VDM Biochemicals | 0330-2528181 |
sales@vdmbio.com | United States | 510 | 64 |
Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 |
info@hanhongsci.com | China | 42982 | 64 |
Chemsky (shanghai) International Co.,Ltd | 021-50135380 |
shchemsky@sina.com | China | 15421 | 60 |