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T-2 TOXIN

T-2 TOXIN 구조식 이미지

카스 번호:: 21259-20-1

상품명:: T-2 TOXIN

동의어(영문):: toxint2;Toxin T 2;hothecene;nsc138780;T-2 TOXIN;T-2 toxins;alerate[qr];FUSARITOXIN;t-2mycotoxin;Insariotoxin

CBNumber:: CB6469458

분자식:: C24H34O9

포뮬러 무게:: 466.53

MOL 파일:: 21259-20-1.mol

속성

안전

용도

공급 업체 116

T-2 TOXIN 속성

녹는점: 151.5℃

알파: D26 +15° (c = 2.58 in ethanol)

끓는 점: 489.35°C (rough estimate)

밀도: 1.1942 (rough estimate)

굴절률: 1.6230 (estimate)

인화점: 2 °C

저장 조건: −20°C

용해도: DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml

물리적 상태: 가루

산도 계수 (pKa): 13.24±0.70(Predicted)

색상: 하얀색

Merck: 13,9872

IARC: 3 (Vol. 31, Sup 7) 1987

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

위험품 표기	T+,T,Xn,F
위험 카페고리 넘버	26/27/28-38-36-20/21/22-11
안전지침서	28-36/37-45-36-26-16-36/37/39-22
유엔번호(UN No.)	UN 3462 6.1/PG 1
WGK 독일	3
RTECS 번호	YD0100000
F 고인화성물질	10-21
위험 등급	6.1(a)
포장분류	I
HS 번호	29329990
유해 물질 데이터	21259-20-1(Hazardous Substances Data)
독성	LD50 orally in female rats: 4.0 mg/kg (Marasas); LD50 (mg/kg) in mice: 5.2 i.p., 4.2 i.v.; in rats: 7.0 intragastric, 0.9-1.3 i.p., 0.9 i.v., 2.0 s.c.; in guinea pigs: 3.0-4.0 orally, 5.3 intragastric, 1.0 i.m., 1.0-2.0 i.v., 1.0-2.0 s.c.; in pigs: 5.0 orally, 3.0 i.v. (Yagen, Bailer)

그림문자(GHS):

신호 어:

Danger

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드
H315	피부에 자극을 일으킴	피부부식성 또는 자극성물질	구분 2	경고		P264, P280, P302+P352, P321,P332+P313, P362

예방조치문구:

P262	눈, 피부, 의복에 묻지 않도록 하시오.
P280	보호장갑/보호의/보안경/안면보호구를 착용하시오.

NFPA 704

	0
4		0

T-2 TOXIN C화학적 특성, 용도, 생산

개요

T-2 toxin is a trichothecene mycotoxin that has been found in Fusarium. It binds to and inhibits peptidyltransferase in the 60S ribosomal subunit, inducing a ribotoxic stress response that triggers JNK and p38 MAPK signaling. T-2 toxin (3 nM) decreases toll-like receptor expression and LPS-induced production of IL-1β, TNF-α, and nitric oxide (NO) in, and is cytotoxic to (IC₅₀ = 19.47), primary pig alveolar macrophages (PAMs). In vivo, T-2 toxin induces production of reactive oxygen species (ROS), lipid peroxidation, and glutathione (GSH) depletion in mouse brain and is lethal to mice (LD₅₀s = 1.54-5.94 mg/kg). It also induces hepatocyte apoptosis and dyslipidemias in mice. T-2 toxin has been found in Fusarium-infected wheat, barley, and rice crops both in fields and in storage.

화학적 성질

White powder

용도

T-2 Toxin is a tricothecene mycotoxin produced by fungi of the genus Fusarium. T-2 Toxin induces DNA damage and cell death on prolonged administration.

일반 설명

T-2 Toxin is found to be a potent trichothecene mycotoxin produced by the genus fusarium fungi in feedstuffs and cereal grains.

Safety Profile

Poison by ingestion, intramuscular, subcutaneous, intraperitoneal, intracerebral, and intravenous routes. Moderately toxic by inhalation. Experimental teratogenic and reproductive effects. A skin irritant. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

T-2 TOXIN 준비 용품 및 원자재

원자재

준비 용품

NEOSOLANIOL

T-2 TOXIN 공급 업체

글로벌( 116)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	6000	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21689	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10326	58
HONG KONG IPURE BIOLOGY CO.,LIMITED	86 18062405514 18062405514	ada@ipurechemical.com	CHINA	3465	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33350	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	4398	58

T-2 TOXIN 관련 검색:

제랄레논 테트라하이드로-4-메틸-2-(2-메틸-1-프로페닐)-2H-피란 Toxin HT 2,T-2, Toxin analog toxin,bluegreenalga,microcystisaeruginos TRANS-1,4-CYCLOHEXENEDIOL T-2 TOXIN DIACETOXYSCIRPENOL NEOSOLANIOL deacetyl-ht-2toxi scirpentriol T-2 TETRAOL VERRUCAROL gb2toxi entero-toxin(staphylococcusreduced PERTUSSIS TOXIN BRP DIPHTHERIA TOXIN BRP - * BIOTOX 1KTX SCORPION TOXIN SHK TOXIN