N,O-비스(트리메틸시릴)아세트아마이드
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N,O-비스(트리메틸시릴)아세트아마이드 속성
- 녹는점
- 24 °C
- 끓는 점
- 71-73 °C35 mm Hg(lit.)
- 밀도
- 0.832 g/mL at 20 °C(lit.)
- 증기압
- 10 hPa (50 °C)
- 굴절률
- n
20/D 1.417(lit.)
- 인화점
- 53 °F
- 저장 조건
- Store below +30°C.
- 용해도
- 많은 비극성 및 극성 비양성자성 용매와 섞일 수 있습니다.
- 물리적 상태
- 결정질 분말, 결정 및/또는 덩어리
- 산도 계수 (pKa)
- 5.82±0.50(Predicted)
- Specific Gravity
- 0.832
- 색상
- 연한 노란색 또는 베이지색에서 갈색까지
- 감도
- Moisture Sensitive
- Hydrolytic Sensitivity
- 7: reacts slowly with moisture/water
- BRN
- 1306669
- CAS 데이터베이스
- 10416-59-8(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | C,Xn,F | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 10-14-22-34-40-20/21/22-11 | ||
| 안전지침서 | 26-36/37/39-45-7/8-43A-36-30-23-16-7/9 | ||
| 유엔번호(UN No.) | UN 2920 8/PG 2 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | AK3000000 | ||
| F 고인화성물질 | 10-21 | ||
| TSCA | Yes | ||
| 위험 등급 | 8 | ||
| 포장분류 | II | ||
| HS 번호 | 29310095 | ||
| 독성 | LD50 orally in Rabbit: 1580 mg/kg | ||
| 기존화학 물질 | KE-34679 |
N,O-비스(트리메틸시릴)아세트아마이드 C화학적 특성, 용도, 생산
물리적 성질
bp 71–73°C/35 mmHg.용도
N,O-Bis(trimethylsilyl)acetamide is a powerful silylating agent; reacts with a wide range of functional groups.BSA was used to trimethylsilylate the hydroxyl group of 12 selectively to form in almost quantitative yield (eq 32).The presence of catalytic amounts (～0.02 equiv) of tetrabutylammonium fluoride (TBAF) significantly promoted the silylation of alcohols under mild conditions with high chemoselectivity, i.e., TBAF plays a role as a smooth silyl transfer catalyst from nitrogen to the hydroxyl group.
제조 방법
made by the reaction of acetamide with a large excess of chlorotrimethylsilane in the presence of triethylamine.일반 설명
N,O-Bis(trimethylsilyl)acetamide is an excellent silylation reagent. For some sterically hindered primary or secondary nitro compounds, N,O-bis(trimethylsilyl)acetamide and BSTFA achieve better results than normal silylation conditions.Purification Methods
Fractionate it through a spinning band column and collect liquid b 71-73o/35mm, and not higher because the main impurity MeCONHSiMe3 distils at b 105-107o/35mm. It is used for derivatising alcohols and sugars [Klebe et al. J Am Chem Soc 88 3390 1966, see Matsuo et al. Carbohydr Res 241 209 1993, Johnson Carbohydr Res 237 313 1992]. Itis FLAMMABLE and TOXIC.N,O-비스(트리메틸시릴)아세트아마이드 준비 용품 및 원자재
원자재
준비 용품
N-Methyl-N-(trimethylsilyl)trifluoroacetamide
N-(Trimethylsilyl)-2-[(trimethylsilyl)oxy]pyrimidin-4-amine
2-METHYL-1-(TRIMETHYLSILOXY)-1-PROPENE
1-Cyclohexenyloxytrimethylsilane
1-(Trimethylsiloxy)cyclopentene
β-D-Glucopyranose, 1,6-anhydro-2,3,4-tris-O-(trimethylsilyl)-
[(11-Fluoroundecyl)oxy]trimethylsilane
Pyrimidine, 5-methyl-4-[(trimethylsilyl)oxy]-2-[(trimethylsilyl)thio]-
N,O-비스(트리메틸시릴)아세트아마이드 공급 업체
글로벌( 637)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5993 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 8174 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15932 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 |
jack.li@time-chemicals.com | China | 1807 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
N,O-비스(트리메틸시릴)아세트아마이드 관련 검색:
아세트아미노펜 N,N-디메틸아세트아미드 2-시아노아세트아미드 싸이오아세트아마이드 아세트아마이드 터트-뷰틸클로로다이메틸실란 로우 B-12 휴먼 세룸 알부민 트라이메틸실레인 N,O-비스(트리메틸시릴)아세트아마이드
N-(Trimethylsilyl)acetamide
2,2,2-TRIFLUORO-N,O-BIS(TRIMETHYLSILYL)-ACETAMIDE,Trifluoro-N,O-bis(trimethylsilyl)acetamide,N,O-bis(trimethylsilyl)acetamide,*with 10%
N,N'-Dimethyl-1,2-ethanediamine
N,N'-Methylenebisacrylamide
N,N-Bis(2-cyanoethyl)formamide
TERT-BUTYL N-(TERT-BUTOXYCARBONYLOXY)CARBAMATE
N,N'-BIS(3-AMINOPROPYL)ETHYLENEDIAMINE
2,2-Bis(trimethylsilyl)acetamide
2,2,2-trifluoro-N,N-bis(trimethylsilyl)-Acetamid