ASIALOGANGLIOSIDE-GM2

ASIALOGANGLIOSIDE-GM2 구조식 이미지
카스 번호:
35960-33-9
상품명:
ASIALOGANGLIOSIDE-GM2
동의어(영문):
GG3;ASIALO GM2;Glycolipid GA2;GA2 GANGLIOSIDE;Ganglioside GA2;gangliosides (Gls);Tay-Sachs globoside;CERAMIDE TRIHEXOSIDE;ASIALOGANGLIOSIDE-GM2;Glycosphingolipid GA2
CBNumber:
CB8124322
분자식:
C56H104N2O18
포뮬러 무게:
1093.42756
MOL 파일:
35960-33-9.mol

ASIALOGANGLIOSIDE-GM2 속성

저장 조건
−20°C
용해도
Chloroform:Methanol:Water (2:1:0.1): Soluble
물리적 상태
동결건조된 분말

안전

WGK 독일 3

ASIALOGANGLIOSIDE-GM2 C화학적 특성, 용도, 생산

개요

Ganglioside GM2 asialo (asialo- GM2) is a glycosphingolipid containing three monosaccharide residues and a fatty acid of variable chain length but lacking the sialic acid residue present on ganglioside M2. Asialo-GM2 levels are low-to-undetectable in normal human brain, but it accumulates in the brain of patients with Tay-Sachs and Sandhoff disease, which are neurodegenerative disorders characterized by deficiency of lysosomal β-hexosaminidase A and B, respectively. It also binds to various bacteria, including Pseudomonas isolates derived from cystic fibrosis patients. Asialo-GM2 mixture contains ganglioside GM2 asialo molecular species with fatty acyl chains of variable lengths. [Matreya, LLC. Catalog No. 1512]

용도

Ganglioside GM2, Asialo is a semisynthetic ganglioside.

일반 설명

Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum; contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage; for classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980.

ASIALOGANGLIOSIDE-GM2 준비 용품 및 원자재

원자재

준비 용품


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