Fexofenadine-d10 Hydrochloride

Fexofenadine-d10 Hydrochloride C화학적 특성, 용도, 생산

개요

Fexofenadine-d₁₀ is intended for use as an internal standard for the quantification of fexofenadine by GC- or LC-MS. Fexofenadine is a histamine H₁ receptor antagonist (K_i = 10 nM). It reverses contraction of isolated rat tracheal strips induced by acetyl-β-methylcholine . Fexofenadine inhibits expression of IL-8 in TNF-α-stimulated HCT116 and COLO 205 cells. Oral administration of fexofenadine (2 and 10 mg/kg) reduces severity of colitis and phospho-IκB kinase activation in a mouse model of colitis induced by dextran sulfate sodium (DSS; ).

용도

Fexofenadine-d10 Hydrochloride is the labeled analogue of Fexofenadine Hydrochloride (F322490), the active metabolite of Terfenadine (T114500), a H1-histamine receptor antagonist.

Fexofenadine-d10 Hydrochloride 준비 용품 및 원자재

원자재

준비 용품

Fexofenadine-d10 Hydrochloride 공급 업체

공급자	전화	이메일	국가	제품 수	이점
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Cato Research Chemicals Inc.	020-81960175	min.he@cato-chem.com	China	1958	55
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	56026	58
Hefei Molake Biotechnology Co., Ltd.	0551-66336380 18956014586	983438788@qq.com	China	2093	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44843	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8740	58
Nanjing Shizhou Biology Technology Co.,Ltd	17301488900	judy.xia@synzest.com	China	12584	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 15850508050	rose.shi@synzest.com	China	6210	58
SHANGHAI ZZBIO CO., LTD.	021-58979353 18019707223	tech@zzbioco.com	China	12065	58