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Dimetacrine

Dimetacrine 구조식 이미지

카스 번호:: 4757-55-5

상품명:: Dimetacrine

동의어(영문):: Dimetacrine;dimethacrine;10(9H)-AcridinepropanaMine,N,N,9,9-tetraMethyl-;9,9-Dimethyl-10-[3-(dimethylamino)propyl]acridan;3-(9,9-dimethylacridin-10-yl)propyl-dimethyl-amine;3-(9,9-dimethylacridin-10-yl)-N,N-dimethylpropan-1-amine;3-(9,9-dimethylacridin-10-yl)-N,N-dimethyl-propan-1-amine;9,10-Dihydro-9,9-dimethyl-10-(3-dimethylaminopropyl)acridine

CBNumber:: CB91103240

분자식:: C20H26N2

포뮬러 무게:: 294.43

MOL 파일:: 4757-55-5.mol

속성

안전

용도

공급 업체 11

Dimetacrine 속성

끓는 점: bp1 200°

밀도: 0.9927 (rough estimate)

굴절률: 1.5640 (estimate)

저장 조건: Store at -20°C

용해도: DMSO에 용해됨

산도 계수 (pKa): 9.49±0.28(Predicted)

안전

Dimetacrine C화학적 특성, 용도, 생산

Originator

Isotonil,Siegfried,W. Germany,1967

Manufacturing Process

A mixture of 10.0 g of 5.5-dimethylacridan, 2.0 g of pulverized sodium amide and 6.5 g of 1-chloro-3-dimethylaminopropane in 50 ml of xylene is heated at reflux with stirring for one hour. To the cooled reaction mixture is added one volume of water. The organic layer is separated and extracted several times with diluted lactic acid. The acidic extracts are combined, washed with ether and neutralized by alkali. The crude 10-(3'-dimethylaminopropyl)-5,5- dimethylacridan is isolated by ether extraction and purified by distillation in a high vacuum. The yield is 6.4 g BP 170°-180°C/0.005mm. nD29 = 1.5990.
43 g of the base I are dissolved in 229 ml of 1 N aqueous d-tartaric acid and the clear solution so obtained is evaporated to dryness under reduced pressure. The residue is dissolved in 150 ml of 90% ethanol which solution after cooling gives the tartaric acid salt of I in white needles. The salt contains 1 mol of tartaric acid per 1 mol of the base. MP 155°-156°C. Easily soluble in cold water.

Therapeutic Function

Antidepressant

Dimetacrine 준비 용품 및 원자재

원자재

1-Chloro-3-Dimethylaminopropane 나트륨아미드 비천연형 D(-)주석산

준비 용품

Dimetacrine 공급 업체

글로벌( 11)공급 업체

공급자	전화	이메일	국가	제품 수	이점
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23556	58
Shaanxi Didu New Materials Co. Ltd	+86-89586680 +86-13289823923	1026@dideu.com	China	9020	58
Chemwill Asia Co.,Ltd.	86-21-51086038	chemwill_asia@126.com	CHINA	23931	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840	psaitong@jm-bio.com	China	29778	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24018	58

Dimetacrine 관련 검색:

Monometacrine Dimetacrine