Tigemonam

Tigemonam 구조식 이미지
카스 번호:
102507-71-1
상품명:
Tigemonam
동의어(영문):
Tigemom;SQ-30213;Tigemonam;Antibiotic SQ-30213;[[[(Z)-1-(2-Aminothiazol-4-yl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-(sulfooxy)azetidin-3-yl]amino]-2-oxoethylidene]amino]oxy]acetic acid;2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-sulfooxyazetidin-3-yl]amino]-2-oxoethylidene]amino]oxyaceticaci;Acetic acid, 2-[[(Z)-[1-(2-amino-4-thiazolyl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-;Sulfuric acid [(3S)-3-[[2-(2-aminothiazol-4-yl)-2-[(Z)-carboxymethyloxyimino]-1-oxyethyl]amino]-4,4-dimethyl-2-oxoazetidin-1-yl] ester
CBNumber:
CB91179920
분자식:
C12H15N5O9S2
포뮬러 무게:
437.41
MOL 파일:
102507-71-1.mol

Tigemonam 속성

밀도
1.91±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMSO에 용해됨
산도 계수 (pKa)
-3?+-.0.18(Predicted)

안전

Tigemonam C화학적 특성, 용도, 생산

Clinical Use

Tigemonam is a newer monobactam that is orally active.It is highly resistant to β-lactamases. The antibacterialspectrum of activity resembles that of aztreonam. It is veryactive against the Enterobacteriaceae, including E. coli,Klebsiella, Proteus, Citrobacter, Serratia, and Enterobacterspp. It also exhibits good potency against H. influenzae andN. gonorrhoeae. Tigemonam is not particularly activeagainst Gram-positive or anaerobic bacteria and is inactiveagainst P. aeruginosa.
In contrast to the poor oral bioavailability of aztreonam,the oral absorption of tigemonam is excellent. Itcould become a valuable agent for the oral treatment ofurinary tract infections and other non–life-threatening infectionscaused by β-lactamase–producing Gram-negativebacteria.

Tigemonam 준비 용품 및 원자재

원자재

준비 용품


Tigemonam 공급 업체

글로벌( 11)공급 업체
공급자 전화 이메일 국가 제품 수 이점
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 19892 58
MedChemexpress LLC 021-58955995
sales@medchemexpress.cn United States 4863 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312
liming@bio-fount.com China 9730 58
Beijing xinyanhui pharmaceutical research and development co., LTD 13969155946
1461866103@qq.com China 16111 58
Taizhou Nanfeng Pharmaceutical Research Institute 12345678910
nanfengdrug@163.com China 15323 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24131 58
Hubei Chenghai Chemical Co., Ltd 027-59220433 18327245847
112699200@qq.com China 9993 58
RD International Technology Co., Limited 18988968278
sales@ubiochem.com China 9146 58

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