LINDERANE

LINDERANE 구조식 이미지
카스 번호:
13476-25-0
상품명:
LINDERANE
동의어(영문):
linerane;LINDERANE;LINDERANE(RG);wuyaomineizhi;Linderane ,98%;Linderane, 98%, from Lindera aggregata (Sims) Kosterm.;(1aS,4E,10S,10aS)-3,6,10,10a-Tetrahydro-5,9-dimethyl-2H-10,1a-(epoxymethano)oxireno[4,5]cyclodeca[1,2-b]furan-12-one;(1aS,4E,10S,10aS)-3,6,10,10a-Tetrahydro-5,9-dimethyl-10,1a-(epoxymethano)-2H-oxireno[4,5]cyclodeca[1,2-b]furan-12-one;2H-10,1a-(Epoxymethano)oxireno[4,5]cyclodeca[1,2-b]furan-12-one,3,6,10,10a-tetrahydro-5,9-dimethyl-, (1aS,4E,10S,10aS)-
CBNumber:
CB9243408
분자식:
C15H16O4
포뮬러 무게:
260.29
MOL 파일:
13476-25-0.mol
MSDS 파일:
SDS

LINDERANE 속성

녹는점
190~191℃
끓는 점
434.5±45.0 °C(Predicted)
밀도
1.30±0.1 g/cm3(Predicted)
저장 조건
-20°C
용해도
클로로포름(약간 용해됨), DMSO(약간 용해됨), 메탄올(약간 용해됨)
물리적 상태
고체
물리적 상태
단단한 모양
색상
흰색에서 황백색까지
안정성
흡습성

안전

안전지침서 24/25
HS 번호 29322090

LINDERANE C화학적 특성, 용도, 생산

개요

Linderane is a sesquiterpene that has been found in L. aggregata. It inhibits the cytochrome P450 (CYP) isoform CYP2C9 (Ki = 1.26 μM) in an irreversible and NADPH-dependent manner. Linderane decreases phosphoenolpyruvate carboxykinase (Pck1) and glucose-6-phosphatase (G6pc) gene expression, cAMP concentration, and CREB phosphorylation, increases phosphodiesterase 3 (PDE3) activity, and inhibits gluconeogenesis in rat primary hepatocytes. In vivo, linderane (50 mg/kg twice per day) decreases serum and hepatic triglyceride levels, as well as random-fed and fasting blood glucose levels in ob/ob mice.

용도

Linderane is a sequiterpene lactone extract from Lindera strychnifolia compound used as a cytotoxic agent against hepaic stellate cells.

LINDERANE 준비 용품 및 원자재

원자재

준비 용품


LINDERANE 공급 업체

글로벌( 180)공급 업체
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Henan Tianfu Chemical Co.,Ltd.
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Shanghai Zheyan Biotech Co., Ltd.
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career henan chemical co
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Hubei Jusheng Technology Co.,Ltd.
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Chongqing Chemdad Co., Ltd
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Shanghai Standard Technology Co., Ltd.
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Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879
sales@chemnorm.com CHINA 2935 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671
sales@tnjchem.com China 34572 58

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